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LEE Kwangho, NIU Deqiang, PETTER Russell C, BAEVSKY Matthew Frank, SINGH Juswinder: COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS, HETEROCYCLIC COMPOUNDS AND USES THEREOF. AVILA THERAPEUTICS, LEE Kwangho, NIU Deqiang, PETTER Russell C, BAEVSKY Matthew Frank, SINGH Juswinder, BUTEAU Kristen C, May 10, 2012: WO/2012/061299 (32 worldwide citation)

Heterocyclic pyrimidine compounds that modulate mutant-selective epidermal growth factor receptor (EGFR) kinase activity are disclosed. Selectivity in inhibition of various mutant-EGFR is disclosed. Pharmaceutical compositions containing the pyrimidine derivatives, and methods of treating diseases a ...


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CASTRO Alfredo C, EVANS Catherine A, JANARDANANNAIR Somarajannair, LESCARBEAU Andre, LIU Tao, SNYDER Daniel A, TREMBLAY Martin R, REN Pingda, LIU Yi, LI Liansheng, CHAN Katrina: [fr] COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS, [en] HETEROCYCLIC COMPOUNDS AND USES THEREOF. CASTRO Alfredo C, EVANS Catherine A, JANARDANANNAIR Somarajannair, LESCARBEAU Andre, LIU Tao, SNYDER Daniel A, TREMBLAY Martin R, REN Pingda, LIU Yi, LI Liansheng, CHAN Katrina, INFINITY PHARMACEUTICALS, INTELLIKINE, INSOGNA Anthony M, March 7, 2013: WO/2013/032591 (25 worldwide citation)

[en] Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI 3 kinase activity, are described herein.


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CHEN Yi, CUSHING Timothy D, FISHER Benjamin, GONZALEZ LOPEZ DE TURISO Felix, HAO Xiaolin, SHIN Youngsook: COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS, HETEROCYCLIC COMPOUNDS AND THEIR USES. AMGEN, CHEN Yi, CUSHING Timothy D, FISHER Benjamin, GONZALEZ LOPEZ DE TURISO Felix, HAO Xiaolin, SHIN Youngsook, PERSON Richard V, June 28, 2012: WO/2012/087784 (24 worldwide citation)

Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammat ...


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CASTRO Alfredo C, EVANS Catherine A, JANARDANANNAIR Somarajannair, LESCARBEAU Andre, LIU Tao, SNYDER Daniel A, TREMBLAY Martin R, REN Pingda, LIU Yi, LI Liansheng, CHAN Katrina: [fr] COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS, [en] HETEROCYCLIC COMPOUNDS AND USES THEREOF. CASTRO Alfredo C, EVANS Catherine A, JANARDANANNAIR Somarajannair, LESCARBEAU Andre, LIU Tao, SNYDER Daniel A, TREMBLAY Martin R, REN Pingda, LIU Yi, LI Liansheng, CHAN Katrina, INFINITY PHARMACEUTICALS, INTELLIKINE, INSOGNA Anthony M, January 24, 2013: WO/2013/012915 (20 worldwide citation)

[en] Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.


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REN Pingda, LIU Yi, LI Liansheng, CHAN Katrina, WILSON Troy Edward, CAMPBELL Simon Fraser: Composés hétérocycliques et leurs utilisations, Heterocyclic compounds and uses thereof. Intellikine, REN Pingda, LIU Yi, LI Liansheng, CHAN Katrina, WILSON Troy Edward, CAMPBELL Simon Fraser, WILLIS Michael A, December 1, 2011: WO/2011/149937 (14 worldwide citation)

Heterocyclic entities that modulate PI3 kinase activity, pharmaceutical compositions containing the heterocyclic entities, and methods of using these chemical entities for treating diseases and conditions associated with PI3 kinase activity are described herein.


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REN Pingda, LIU Yi, LI Liansheng, CHAN Katrina, WILSON Troy Edward, CAMPBELL Simon Fraser: COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS, HETEROCYCLIC COMPOUNDS AND USES THEREOF. INTELLIKINE, REN Pingda, LIU Yi, LI Liansheng, CHAN Katrina, WILSON Troy Edward, CAMPBELL Simon Fraser, ORBAI Lucian, August 30, 2012: WO/2012/116237 (13 worldwide citation)

Heterocyclic entities that modulate PI3 kinase activity, pharmaceutical compositions containing the heterocyclic entities, and methods of using these chemical entities for treating diseases and conditions associated with PI3 kinase activity are described herein.


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KOGAN Vladimir, LURYA Leonid, TABACHNIK Lev: [fr] COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS DANS LE TRAITEMENT DE TROUBLES SEXUELS. ATIR HOLDING, KOGAN Vladimir, LURYA Leonid, TABACHNIK Lev, GE EHRLICH, October 18, 2012: WO/2012/140642 (3 worldwide citation)

[en] Biologically active compounds, which are useful for treating a sexual disorder, are provided herein. Further provided are pharmaceutical compositions formulated for transdermal composition, which comprise a biologically active compound useful for treating a sexual disorder. The compounds and ph ...


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CHEN YI , CUSHING TIMOTHY D , DUQUETTE JASON A , GONZALEZ LOPEZ DE TURISO FELIX , HAO XIAOLIN , HE XIAO , LUCAS BRIAN , MCGEE LAWRENCE R , REICHELT ANDREAS , SEGANISH JENNIFER , SHIN YOUNGSOOK , ZHANG DAWEI : [de] HETEROCYCLISCHE VERBINDUNGEN UND IHRE ANWENDUNGEN, [en] HETEROCYCLIC COMPOUNDS AND THEIR USES, [fr] COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS. AMGEN  , July 20, 2016: EP3045458-A1

[en] Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with infl ...


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TWOROWSKI DMITRY, MATSIEVITCH RON, KOGAN VLADIMIR: [fr] COMPOSÉS HÉTÉROCYCLIQUES ET LEURS UTILISATIONS DANS LE TRAITEMENT DE TROUBLES SEXUELS. ATIR HOLDING, September 29, 2010: EP2233472-A1

[en] The present invention concerns novel heterocyclic compounds, which exhibit a dopamine receptor (preferably a D4 receptor) agonistic activity, and/or a PDE5 inhibitory activity, a pharmaceutical composition containing same and uses thereof in the treatment of sexual disorders such as decreased l ...