51
Michael P Nova, Hanan Potash, Xiao Yi Xiao, Zahra Parandoosh, Gary S David: Method for tagging and screening molecules. Discovery Partners International, Kilpatrick Stockton, November 20, 2001: US06319668 (218 worldwide citation)

Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions. The matrix material ...


52
R Fabian Pease, Glenn McGall, Martin J Goldberg, Richard P Rava, Stephen P A Fodor, Virginia Goss, Lubert Stryer, James L Winkler: Printing molecular library arrays using deprotection agents solely in the vapor phase. Affymetrix, Townsend & Townsend & Crew, February 4, 1997: US05599695 (217 worldwide citation)

A method and apparatus for selectively applying a print material onto a substrate for the synthesis of an array of oligonucleotides at selected regions of a substrate. The print material includes a barrier material, a monomer sequence, a nucleoside, a deprotection agent, a carrier material, among ot ...


53
David K Wong, Kenneth M Curry: Calibration solutions useful for analysis of biological fluids and methods employing same. Via Medical Corporation, Stephen E Reiter, Pretty Schroeder Brueggemann & Clark, April 9, 1996: US05505828 (216 worldwide citation)

Novel calibration solutions are provided which are useful, for example, with sensor assemblies used for analysis of CO.sub.2, and optionally, for concurrent analysis of O.sub.2, especially in combination infusion fluid delivery/blood chemistry analysis systems which include a sensor assembly with ea ...


54
Michael P Nova, Zahra Parandoosh, Andrew E Senyei, Xiao Yi Xiao, Gary S David, Yozo Satoda, Chanfeng Zhao, Hanan Potash: Matrices with memories and uses thereof. Irori, Brown Martin Haller & McClain, October 5, 1999: US05961923 (214 worldwide citation)

Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions. The matrix material ...


55
David R Walt, Karri L Michael: Target analyte sensors utilizing microspheres. Trustees of Tufts College Tufts University, Dorsey & Whitney, Robin M Silva, David C Foster, February 22, 2005: US06859570 (203 worldwide citation)

A microsphere-based analytic chemistry system and method for making the same is disclosed in which microspheres or particles carrying bioactive agents may be combined randomly or in ordered fashion and dispersed on a substrate to form an array while maintaining the ability to identify the location o ...


56
Joel S Douglas, Karen R Drexler, James N Wilson: Devices for testing for the presence and/or concentration of an analyte in a body fluid. Roche Diagnostics Operations, Woodard Emhardt Moriarty McNett & Henry, November 16, 2004: US06818180 (202 worldwide citation)

Devices and methods for utilizing dry chemistry dye indicator systems for body fluid analysis such as glucose level in whole blood are provided by incorporating a porous membrane with a skin side which enables separation of whole blood and visually reading the indicator without removing the red bloo ...


57
Ulrich Wiesner, Hooisweng Ow, Daniel R Larson, Watt W Webb: Fluorescent silica-based nanoparticles. Cornell Research Foundation, Harris Beach PLLC, October 30, 2012: US08298677 (196 worldwide citation)

The invention generally relates to fluorescent nanoparticles and more specifically to silica-based fluorescent nanoparticles of less than 30 nm with covalently attached organic dyes. The invention provides a fluorescent monodisperse silica nanoparticle comprising fluorophore center core and a silica ...


58
Mei Chang, David N K Wang, John M White, Dan Maydan: Inlet manifold and methods for increasing gas dissociation and for PECVD of dielectric films. Applied Materials, Flehr Hohbach Test Albritton & Herbert, August 8, 1989: US04854263 (192 worldwide citation)

An inlet gas manifold for a vacuum deposition chamber incorporates inlet apertures which increase in diameter or cross-section transverse to the direction of gas flow. The aperture configuration increases the dissociation gases such as nitrogen and, thus increases the rate of silicon nitride deposit ...


59
Uziel Landau, John J D Urso, David B Rear: Electro deposition chemistry. Applied Materials, Thomason Moser & Patterson, September 5, 2000: US06113771 (190 worldwide citation)

The present invention provides plating solutions, particularly metal plating solutions, designed to provide uniform coatings on substrates and to provide substantially defect free filling of small features, e.g., micron scale features and smaller, formed on substrates with none or low supporting ele ...


60
Michael Kwan, Eric Liu: Gas chemistry cycling to achieve high aspect ratio gapfill with HDP-CVD. Applied Materials, Townsend & Townsend & Crew, January 1, 2002: US06335288 (190 worldwide citation)

A method and apparatus are disclosed for depositing a dielectric film in a gap having an aspect ratio at least as large as 6:1. By cycling the gas chemistry of a high-density-plasma chemical-vapor-deposition system between deposition and etching conditions, the gap may be substantially 100% filled. ...