1
Yasushi Nakagawa, Takashi Ito: Chemically modified protein with polyethyleneglycol. Takeda Chemical, Wegner & Bretschneider, December 13, 1988: US04791192 (352 worldwide citation)

The chemically modified protein of the present invention has a strong islet-activating activity and is lower in various side effects than non-modified IAP, so that it may be employed as a prevention and therapeutic drug for diabetes.


2
RECOMBINANT HUMAN INTERFERON-LIKE PROTEINS. January 19, 2017: US20170015723-A1

This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology in described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon like alpha 2b (HuIFN-α2 ...


3
RECOMBINANT HUMAN INTERFERON-LIKE PROTEINS. March 14, 2019: US20190077843-A1

This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human inteferon like alpha 2b (HuIFN-α2b ...