1
Kwang Nho, Shmuel Zalipsky, Frank Davis: Chemically modified hemoglobin as an effective, stable non-immunogenic red blood cell substitute. Enzon, Lerner David Littenberg Krumholz & Mentlik, August 10, 1993: US05234903 (83 worldwide citation)

The present invention relates to chemically modified hemoglobin produced by a novel and efficient method in which stroma-free hemoglobin is first effectively deoxygenated and reduced and then conjugated with a polyalkylene oxide such as polyethylene glycol (PEG) under conditions which maintain the s ...


2
Kwang Nho, Shmuel Zalipsky, Frank Davis: Chemically modified hemoglobin as an effective, stable, non-immunogenic red blood cell substitute. Enzon, Michael N Mercanti, January 31, 1995: US05386014 (46 worldwide citation)

The present invention relates to chemically modified hemoglobin produced by a novel and efficient method in which stroma-free hemoglobin is first effectively deoxygenated and reduced and then conjugated with a polyalkylene oxide such as polyethylene glycol (PEG) under conditions which maintain the s ...


3
Nho Kwang, Zalipsky Shmuel, Davis Frank: Chemically modified hemoglobin as an effective, stable, non-immunogenic red blood cell substitute. Enzon, MISROCK S Leslie, May 30, 1991: WO/1991/007190

The present invention relates to chemically modified hemoglobin produced by a novel and efficient method in which stroma-free hemoglobin is first effectively deoxygenated and reduced and then conjugated with a polyalkylene oxide such as polyethylene glycol (PEG) under conditions which maintain the s ...


4