1
Henry R Halperin, Ronald D Berger, Ergin Atalar, Elliot R McVeigh, Albert C Lardo, Hugh Calkins, Joao Lima: Brain therapy. Johns Hopkins University School of Medicine, Myers Bigel Sibley & Sajovec P A, August 12, 2008: US07412276 (22 worldwide citation)

A method of performing brain therapy may include placing a subject in a main magnetic field, introducing into the subject's brain a combination imaging and therapeutic probe, the probe including a magnetic resonance imaging antenna and an electrical energy application element, acquiring a first magn ...


2
Jianping Wu, Dwight E Nelson: Electrical brain therapy parameter determination based on a bioelectrical resonance response. Medtronic, Beth L McMahon, December 16, 2014: US08914119 (5 worldwide citation)

Various methods and apparatuses are disclosed that concern delivering electrical stimulation to a brain at a plurality of different stimulation frequencies, sensing one or more bioelectrical signals, and identifying a bioelectrical resonance response of the brain to the electrical stimulation. The b ...


3
Shaker A Mousa, Faith B Davis, Paul J Davis: Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof. NANOPHARMACEUTICALS, Schmeiser Olsen & Watts, February 28, 2017: US09579300 (3 worldwide citation)

Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of t ...


4
Sherwin Hua: Insertion of medical devices through non-orthogonal and orthogonal trajectories within the cranium and methods of using. Knobbe Martens Olson & Bear, May 9, 2017: US09642552

The invention comprises an elongated device adapted for insertion, including self-insertion, through the body, especially the skull. The device has at least one effector or sensor and is configured to permit implantation of multiple functional components through a single entry site into the skull by ...


5
Sherwin Hua: Insertion of medical devices through non-orthogonal and orthogonal trajectories within the cranium and methods of using. Knobbe Martens Olson & Bear, November 21, 2017: US09820668

An elongated device adapted for insertion, including self-insertion, through the body, especially the skull is disclosed. The device has at least one effector or sensor and is configured to permit implantation of multiple functional components through a single entry site into the skull by directing ...


6
Timothy J Denison, Wesley A Santa: Seizure prediction. Medtronic, Shumkaer & Sieffert P A, October 17, 2017: US09788750

Seizure prediction systems and methods include measuring impedance within a brain of a patient to determine whether the brain is in a state indicative of a possibility of an onset of a seizure. In some embodiments, the measured impedance is compared to a predetermined threshold in order to determine ...


7
Steven M Goetz: Brain stimulation programming. Medtronic, Shumaker & Sieffert P A, December 26, 2017: US09849293

A programming system allows a user to program therapy parameter values for therapy delivered by a medical device by specifying a desired therapeutic outcome. In an example, the programming system presents a model of a brain network associated with a patient condition to the user. The model may be a ...


8
J Michael Shifflette, Peter Piferi: Substance delivery devices, systems and methods. MRI Interventions, Myers Bigel P A, February 21, 2017: US09572928

A substance delivery device includes an elongated tubular body having opposing proximal and distal ends, and a diaphragm that is in slideable sealing engagement with an inside wall of the tubular body. The diaphragm is movable in opposite first and second directions within the tubular body. A substa ...


9
Gholam A Peyman: Methods to regulate polarization and enhance function of cells. The Law Office of Patrick F O Reilly III, May 8, 2018: US09962558

Minimally invasive delivery with intercellular and/or intracellular localization of nano- and micro-particle solar cells within and among excitable biological cells to controllably regulate membrane polarization and enhance function of such cells. The cells include retinal and other excitable cells.


10
Gholam A Peyman: Methods to regulate polarization and enhance function of cells. The Law Office of Patrick F O Reilly III, May 1, 2018: US09956425

Methods and compositions to controllably regulate cells at a target site. A quantum dot-targeting agent complex is administered to a patient in need of therapy, and the complex is stimulated using an implanted fiber optic system. In embodiments, the system includes an electrical sensor that detects ...