1
Stephen P A Fodor, Michael C Pirrung, J Leighton Read, Lubert Stryer: Array of oligonucleotides on a solid substrate. Affymax Technologies, Townsend and Townsend Khourie and Crew, August 29, 1995: US05445934 (878 worldwide citation)

A method and apparatus for preparation of a substrate containing a plurality of sequences. Photoremovable groups are attached to a surface of a substrate. Selected regions of the substrate are exposed to light so as to activate the selected areas. A monomer, also containing a photoremovable group, i ...


2
Fan Jian Bing, Hirschhorn Joel N, Huang Xiaohua, Kaplan Paul, Lander Eric S, Lockhart David J, Ryder Thomas, Sklar Pamela: Universal arrays. Whitehead Institute For Biomedical Research, Affymetrix, HOGLE Doreen M, October 5, 2000: WO/2000/058516 (1 worldwide citation)

An array of oligonucleotides on a solid substrate is disclosed, which can be used for multiple purposes. Methods and reagents are provided for performing genotyping to determine the identity or ration of allelic forms of a gene in a sample. A single base extension primer is coupled to a sequence ide ...


3
Jian Bing Fan, Joel N Hirschhorn, Xiaohua Huang, Paul Kaplan, Eric S Lander, David J Lockhart, Thomas Ryder, Pamela Sklar: Universal arrays. Whitehead Institute for Biomedical Research, The General Hospital Corporation, Affymetrix, Lisa M Treannie Esq, Ropes & Gray, April 7, 2005: US20050074787-A1

An array of oligonucleotides on a solid substrate is disclosed, which can be used for multiple purposes. Methods and reagents are provided for performing genotyping to determine the identity or ratio of allelic forms of a gene in a sample. A single base extension primer is coupled to a sequence iden ...


4
Fan Jian Bing, Hirschhorn Joel N, Huang Xiaohua, Kaplan Paul, Lander Eric S, Lockhart David J, Ryder Thomas, Sklar Pamela: Universal arrays. Whitehead Biomedical Inst, Affymetrix, January 2, 2002: EP1165839-A2

An array of oligonucleotides on a solid substrate is disclosed, which can be used for multiple purposes. Methods and reagents are provided for performing genotyping to determine the identity or ration of allelic forms of a gene in a sample. A single base extension primer is coupled to a sequence ide ...


5
THERMAL REACTION DEVICE AND METHOD FOR USING THE SAME. March 15, 2018: US20180073051-A1

A method for carrying out nucleic acid amplification reactions using a microfluidic device is described. Amplification primers and other amplification reagents are deposited at a plurality of reaction sites in the device, a sample solution containing amplifiable polynucleotides is introduced into th ...


6
THERMAL REACTION DEVICE AND METHOD FOR USING THE SAME. August 30, 2018: US20180243741-A1

Devices and methods for performing the relative concentration of a target in a sample, the sample containing both target and non-target components, the method performed by partitioning the sample into a large number of reaction volumes such that the target is concentrated relative to the non-target, ...


7
THERMAL REACTION DEVICE AND METHOD FOR USING THE SAME. June 6, 2019: US20190169676-A1

A method for carrying out nucleic acid amplification reactions using a microfluidic device is described. Amplification primers and other amplification reagents are deposited at a plurality of reaction sites in the device, a sample solution containing amplifiable polynucleotides is introduced into th ...