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Martin James MacPhee, William Nash Drohan, Christoper J Woolverton: Supplemented and unsupplemented tissue sealants, methods of their production and use. The American National Red Cross, Sterne Kessler Goldstein & Fox P L L C, April 25, 2000: US06054122 (213 worldwide citation)

This invention provides a fibrin sealant dressing, wherein said fibrin sealant may be supplemented with at least one composition selected from, for example, one or more regulatory compounds, antibody, antimicrobial compositions, analgesics, anticoagulants, antiproliferatives, anti-inflammatory compo ...


12
Stuart D Edwards: Novasys Medical, Michael A Glenn, Glenn Patent Group, February 5, 2008: US07326235 (171 worldwide citation)

The invention provides a method and system for treating disorders in parts of the body. A particular treatment can include on or more of, or some combination of: ablation, nerve modulation, three-dimensional tissue shaping, drug delivery, mapping stimulating, shrinking and reducing strain on structu ...


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Jacques Y Gauthier, Cheuk K Lau, Yves LeBlanc, Chun Sing Li, Patrick Roy, Michel Therien, Zhaoyin Wang: Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents. Merck Frosst Canada, Curtis C Panzer, David L Rose, September 3, 1996: US05552422 (162 worldwide citation)

The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. ##STR1## The invention also encomp ...


14
Stuart D Edwards: Novasys Medical, Michael A Glenn, Glenn Patent Group, February 17, 2004: US06692490 (162 worldwide citation)

The invention provides a method and system for treating disorders of the genito-urinary tract and other disorders in other parts of the body. A particular treatment can include one or more of, or some combination of ablation, nerve modulation, three-dimensional tissue shaping, drug delivery, mapping ...


15
Gregory G Gayer, Christopher J Comfort: Method and apparatus for augmentating osteointegration of prosthetic implant devices. Comfort Biomedical, Blakely Sokoloff Taylor & Zafman, April 10, 2001: US06214049 (161 worldwide citation)

Bone augmentation in a mammalian body to enhance the mechanical strength of a prosthesis is provided by reinforcement of bone in the region surrounding the implant device. A number of fibrillar wires are formed on the prosthetic implant device. Formation of the fibrillar wires comprises gauging the ...


16
Daniel Bar Shalom, Kindt Larsen: Controlled release article with pulsatile release. Buhk Meditec A A, Foley & Lardner, May 25, 1993: US05213808 (159 worldwide citation)

An article for controlled delivery of an active substance into an aqueous phase has a first layer containing an active substance, and a second layer of a crystalline polymer matrix and a non-ionic surface active agent, the second layer also containing the same or different active substance substanti ...


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Musser John H, Chakraborty Utpal Ranjan: Anti-inflammatory/anti-allergic compounds.. Usv Pharma, May 21, 1986: EP0181568-A2 (145 worldwide citation)

Compounds of the formula: Ar1 - X - Ar - Z - (R)n min and salts thereof, wherein Ar1 is a nitrogen, sulfur, oxygen heterocyclic ring or aromatic ring; Ar is a phenyl ring or a nitrogen, oxygen or sulfur heterocyclic ring; Ar and Ar1 may be fully substituted or less than fully substituted with H, CH3 ...


19
Frank Kochinke: Methods and drug delivery systems for the treatment of orofacial diseases. Reed Intellectual Property Law Group, July 11, 2006: US07074426 (145 worldwide citation)

This invention relates to methods of treating various orofacial diseases involving inflammation, infection and/or pain, using intratissue controlled release drug delivery systems. More particularly, the invention relates to methods for localized or targeted administration of a sustained release form ...


20
David J Vachon: Implantable stimulation lead having an advanceable therapeutic drug delivery system. Pacesetter, Malcolm J Romano, Harold C Schloss, July 2, 1996: US05531780 (144 worldwide citation)

A pacing lead having a stylet introduced anti-inflammatory drug delivery element advanceable from the distal tip electrode. The element is preferably formed as a moldable biocompatible composite material. The element has a biocompatible matrix material which may be combined with drugs and therapeuti ...



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