1
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Behrad Aria, Ephraim Heller, Phillip John Plante, Mark S Vreeke: Electrochemical analyte. E Heller & Company, Merchant & Gould P C, October 17, 2000: US06134461 (1173 worldwide citation)

An electrochemical analyte sensor formed using conductive traces on a substrate can be used for determining and/or monitoring a level of analyte in in vitro or in vivo analyte-containing fluids. For example, an implantable sensor may be used for the continuous or automatic monitoring of a level of a ...


2
Adam Heller, Benjamin J Feldman, James Say, Mark S Vreeke: Method of using a small volume in vitro analyte sensor. Therasense, Merchant & Gould P C, September 19, 2000: US06120676 (1145 worldwide citation)

A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 .mu.L. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. I ...


3
Adam Heller, Benjamin J Feldman, James Say, Mark S Vreeke: Small volume in vitro analyte sensor. E Heller & Company, Merchant & Gould P C, November 7, 2000: US06143164 (1035 worldwide citation)

A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 .mu.L. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. I ...


4
James Say, Michael F Tomasco, Adam Heller, Yoram Gal, Behrad Aria, Ephraim Heller, Phillip John Plante, Mark S Vreeke: Electrochemical analyte sensor. TheraSense, Merchant & Gould P C, November 19, 2002: US06484046 (1002 worldwide citation)

An electrochemical analyte sensor having conductive traces on a substrate is used to determine a level of analyte in in vitro or in vivo analyte-containing fluids. The electrochemical analyte sensor includes a substrate and conductive material disposed on the substrate, the conductive material formi ...


5
John Bernard Buse, Alan Charles Moses: Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator. TheraSense, Merchant & Gould P C, July 8, 2003: US06591125 (999 worldwide citation)

A region of skin, other than the fingertips, is stimulated. After stimulation, an opening is created in the skin (e.g., by lancing the skin) to cause a flow of body fluid from the region. At least a portion of this body fluid is transported to a testing device where the concentration of analyte (e.g ...


6
James D Causey III, Paul H Kovelman, Richard E Purvis, John J Mastrototaro: Analyte sensor and holter-type monitor system and method of using the same. MiniMed, MiniMed, June 19, 2001: US06248067 (956 worldwide citation)

A Holter-type monitor system includes a remotely located data receiving device, an analyte sensor for producing signal indicative of a characteristic of a user, and a Holter-type recording device. The Holter-type recording device includes a housing, a sensor connector, a processor, and a data port. ...


7
Benjamin J Feldman, Adam Heller, Ephraim Heller, Fei Mao, Joseph A Vivolo, Jeffery V Funderburk, Fredric C Colman, Rajesh Krishnan: Method of manufacturing small volume in vitro analyte sensor. TheraSense, Merchant & Gould P C, September 16, 2003: US06618934 (883 worldwide citation)

A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agen ...


8
James L Say, Henning Sakslund, Michael F Tomasco, Jay D Audett, Hyun Cho, Duane O Yamasaki, Adam Heller: Mass transport limited in vivo analyte sensor. TheraSense, Merchant & Gould P C, November 25, 2003: US06654625 (863 worldwide citation)

An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. ...


9
Benjamin J Feldman, Adam Heller, Ephraim Heller, Fei Mao, Joseph A Vivolo, Jeffery V Funderburk, Fredric C Colman, Rajesh Krishnan: Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator. TheraSense, Merchant & Gould P C, October 8, 2002: US06461496 (844 worldwide citation)

A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agen ...


10
Joseph Gross, Meir Reingewirtz, Moshe George Katz: Device and method of calibrating and testing a sensor for in vivo measurement of an analyte. Elan Corporation, Kathleen L Maher, August 14, 2001: US06275717 (830 worldwide citation)

A method of calibrating an analyte sensor in vivo, by providing a first predetermined stimulus to the sensor when the sensor is applied to a subject to produce a first sensor signal, measuring the first sensor signal, and determining a calibration function based on the first measured sensor signal r ...