1
Frank W Hobbs Jr, Anthony J Cocuzza: Alkynylamino-nucleotides. E I Du Pont de Nemours and Company, George A Frank, September 10, 1991: US05047519 (259 worldwide citation)

Alkynylamino-nucleotides and labeled alkynylamino-nucleotides useful, for example, as chain terminating substrates for DNA sequencing are provided along with several key intermediates and processes for their preparation.


2
Frank W Hobbs Jr, George L Trainor: Alkynylamino-nucleotides. E I Du Pont de Nemours and Company, George A Frank, September 29, 1992: US05151507 (155 worldwide citation)

Alkynylamino-nucleotides and labeled alkynylaminonucleotides useful, for example, as chain terminating substrates for DNA sequencing are provided along with several key intermediates and processes for their preparation. For some applications, longer, hydrophilic linkers are provided.


3
Hobbs Frank Worden Jr, Cocuzza Anthony Joseph: Alkynylamino-nucleotides.. Du Pont, January 7, 1988: EP0251786-A2 (63 worldwide citation)

The invention provides alkynylamino-nucleotides and their labeled derivatives which are useful, for example, as chain terminating substrates for DNA sequencing, along with several key intermediates and processes for their preparation.


4
Jingyue Ju, Zengmin Li, John Robert Edwards, Yasuhiro Itagaki: Massive parallel method for decoding DNA and RNA. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, John P White, Gary J Gershik, Cooper & Dunham, August 1, 2017: US09719139 (1 worldwide citation)

This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analog after the nucleotide analog is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotid ...


5
Jingyue Ju, Zengmin Li, John Robert Edwards, Yasuhiro Itagaki: Massive parallel method for decoding DNA and RNA. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, John P White, Gary J Gershik, Cooper & Dunham, August 8, 2017: US09725480 (1 worldwide citation)

This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analog after the nucleotide analog is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotid ...


6
Jingyue Ju, Zengmin Li, John Robert Edwards, Yasuhiro Itagaki: Massive parallel method for decoding DNA and RNA. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, John P White, Gary J Gershik, Cooper & Dunham, August 1, 2017: US09718852 (1 worldwide citation)

This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analog after the nucleotide analog is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotid ...


7
Jingyue Ju, Zengmin Li, John Robert Edwards, Yasuhiro Itagaki: Massive parallel method for decoding DNA and RNA. THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, John P White, Cooper & Dunham, January 16, 2018: US09868985

This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analog after the nucleotide analog is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotid ...


8
Hobbs Frank Worden Jr, Cocuzza Anthony Joseph: Alcynylamino-nucleotides, Alkynylamino-nucleotides. Hobbs Frank Worden Jr, Cocuzza Anthony Joseph, Nen Life Science Products, SIM & MCBURNEY, September 1, 1998: CA1340022

Alkynylamino-nucleotides and labeledalkynylamino-nucleotides useful, for example, aschain terminating substrates for DNA sequencing areprovided along with several key intermediates andprocesses for their preparation.


9
MASSIVE PARALLEL METHOD FOR DECODING DNA AND RNA. The Trustees of Columbia University in the City of New York, March 30, 2017: US20170088574-A1

This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucle ...


10
MASSIVE PARALLEL METHOD FOR DECODING DNA AND RNA. The Trustees of Columbia University in the City of New York, March 30, 2017: US20170088575-A1

This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucle ...