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Linda Lee, Sam Woo, Peter Ma: Chemically-enhanced primer compositions, methods and kits. LIFE TECHNOLOGIES CORPORATION, July 18, 2017: US09708650

A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and ...


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MASTRANGELO Carlos H, FERNANDEZ Renny E: COMPOSITIONS ET MÉTHODES DE SÉQUENÇAGE DE LADN, COMPOSITIONS AND METHODS FOR SEQUENCING DNA. UNIVERSITY OF UTAH RESEARCH FOUNDATION, MASTRANGELO Carlos H, FERNANDEZ Renny E, LANGER Michael R, May 10, 2012: WO/2012/061726

Provided are compositions and methods for sequencing a target polynucleotide that has been used to generate an elongated polynucleotide having a plurality of segments, each segment corresponding to one of the nucleic acid residues of the target polynucleotide and having a sequence motif. The composi ...


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CHEMICALLY-ENHANCED PRIMER COMPOSITIONS, METHODS AND KITS. February 23, 2017: US20170051342-A1

A composition is provided comprising a negatively charged group, an oligonucleotide sequence and at least none or one nuclease-resistant linkage group to form a chemically-enhanced primer. The chemically-enhanced primer can be used for sequencing and fragment analysis. Methods for synthesizing the p ...


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GENETIC SEQUENCE VERIFICATION COMPOSITIONS, METHODS AND KITS. August 31, 2017: US20170247756-A1

Methods, compositions and kits are described for resequencing, confirming or verifying Next Generation Sequencing (NGS) results with Sanger Sequencing. These methods are particularly useful for samples having very limited quantities such as formalin-fixed, paraffin-embedded (FFPE), Laser Capture Mic ...


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CHEMICALLY-ENHANCED PRIMER COMPOSITIONS, METHODS AND KITS. February 8, 2018: US20180037931-A1

A chemically-enhanced primer is provided comprising a negatively charged moiety (NCM), an oligonucleotide sequence having a) non-nuclease resistant inter-nucleotide linkages or b) at least one nuclease resistance inter-nucleotide linkage. The chemically-enhanced primer can be used for sequencing and ...