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JONES Robert C, LIVAK Kenneth J, MAY Andrew, MIR Alain, PIEPRZYK Martin, QIN Jian, RAMAKRISHNAN Ramesh, SPURGEON Sandra, WANG Jun, ZIMMERMANN Bernhard G: Analyses pour la détection dun génotype, de mutations, et/ou dune aneuploïdie, Assays for the detection of genotype, mutations, and/or aneuploidy. Fluidigm Corporation, JONES Robert C, LIVAK Kenneth J, MAY Andrew, MIR Alain, PIEPRZYK Martin, QIN Jian, RAMAKRISHNAN Ramesh, SPURGEON Sandra, WANG Jun, ZIMMERMANN Bernhard G, HALIDAY Emily M, November 17, 2011: WO/2011/142836 (15 worldwide citation)

The present invention provides amplification-based methods for detection of genotype, mutations, and/or aneuploidy. These methods have broad applicability, but are particularly well-suited to detecting and quantifying target nucleic acids in free fetal DNA present in a maternal bodily fluid sample.


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Daniel D Von Hoff, Robert J Penny: System and method for determining individualized medical intervention for a disease state. Caris MPI, Ramin Akhavan, December 16, 2014: US08914239 (9 worldwide citation)

A system and method for determining individualized medical intervention for a particular disease state, and especially for cancers, that includes the molecular profiling of a biological sample from the patient, determining whether any molecular findings including one or more genes, one or more gene ...


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Sandeep Robert Datta, Alexander B Wiltschko: System and method for automatically discovering, characterizing, classifying and semi-automatically labeling animal behavior and quantitative phenotyping of behaviors in animals. President and Fellows of Harvard College, Nixon Peabody, David S Resnick, Erik Birkeneder, April 19, 2016: US09317743 (8 worldwide citation)

A method for studying the behavior of an animal in an experimental area including stimulating the animal using a stimulus device; collecting data from the animal using a data collection device; analyzing the collected data; and developing a quantitative behavioral primitive from the analyzed data. A ...


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Daniel D Von Hoff, Robert J Penny: System and method for determining individualized medical intervention for a disease state. Caris MPI, Ramin Akhavan, September 9, 2014: US08831890 (8 worldwide citation)

A system and method for determining individualized medical intervention for a particular disease state, and especially for cancers, that includes the molecular profiling of a biological sample from the patient, determining whether any molecular findings including one or more genes, one or more gene ...


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Ehud Y Shapiro, Shai Kaplan, Gregory Linshiz, Tuval Ben Yehezkel, Uri Shabi: System and method for editing and manipulating DNA. YEDA RESEARCH AND DEVELOPMENT, Graeser Associates International, Dvorah Graeser, March 15, 2016: US09286439 (7 worldwide citation)

A system and method for planning, manipulating, processing and editing DNA molecules utilizing a core operation on a given input DNA molecule to produce a targeted DNA molecule.


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Caleb J Kennedy, Niru Chennagiri: Methods and systems for storing sequence read data. Good Start Genetics, Thomas C Meyers, Brown Rudnick, September 30, 2014: US08847799 (7 worldwide citation)

The present invention generally relates to storing sequence read data. The invention can involve obtaining a plurality of sequence reads from a sample, identifying one or more sets of duplicative sequence reads within the plurality of sequence reads, and storing only one of the sequence reads from e ...


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BINDER Robert Lloyd, YOUNGQUIST Robert Scott, XU Jun, JUHLIN Kenton Duane, OSBORNE Rosemarie, HARTMAN Scott Michael: PROCÉDÉS DIDENTIFICATION DAGENTS COSMÉTIQUES POUR DES COMPOSITIONS DE SOINS DE LA PEAU, METHODS FOR IDENTIFYING COSMETIC AGENTS FOR SKIN CARE COMPOSITIONS. THE PROCTER & GAMBLE COMPANY, BINDER Robert Lloyd, YOUNGQUIST Robert Scott, XU Jun, JUHLIN Kenton Duane, OSBORNE Rosemarie, HARTMAN Scott Michael, August 30, 2012: WO/2012/116081 (6 worldwide citation)

Provided are methods for determining functional relationships between a cosmetic agent and a skin tissue condition of interest. Also provided are methods for identifying cosmetic agents that affect a skin aging tissue condition, as well as the use of agents identified by such methods for the prepara ...


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LO Yuk Ming Dennis, CHAN Kwan Chee, CHIU Wai Kwun Rossa, JIANG Peiyong: DÉTECTION DABERRATIONS GÉNÉTIQUES OU MOLÉCULAIRES ASSOCIÉES AU CANCER, DETECTION OF GENETIC OR MOLECULAR ABERRATIONS ASSOCIATED WITH CANCER. THE CHINESE UNIVERSITY OF HONG KONG, LO Yuk Ming Dennis, CHAN Kwan Chee, CHIU Wai Kwun Rossa, JIANG Peiyong, GRIFFITH HACK, June 7, 2012: WO/2012/071621 (6 worldwide citation)

Systems, apparatus, and methods are provided for determining genetic or molecular aberrations in a biological sample from an organism. Biological samples including cell-free DNA fragments are analyzed to identify imbalances in chromosomal regions, e.g., due to deletions and/or amplifications in a tu ...