1
Peter Wilding, Larry J Kricka, Jay N Zemel: Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems. Trustees of the University of Pennsylvania, Dann Dorfman Herrell and Skillman, June 10, 1997: US05637469 (669 worldwide citation)

Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow system that includes a sample flow channel extending from the inlet port. The mesoscale flow system furthe ...


2
Peter Wilding, Larry J Kricka, Jay N Zemel: Apparatus for the detection of an analyte utilizing mesoscale flow systems. The Trustees Of The University Of Pennsylvania, Dann Dorfman Herrell and Skillman P C, February 2, 1999: US05866345 (277 worldwide citation)

Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow system that includes a sample flow channel extending from the inlet port. The mesoscale flow system furthe ...


3
Houghton Michael, Choo Qui Lim, Kuo George: Nanbv diagnostics and vaccines.. Chiron, May 31, 1989: EP0318216-A1 (229 worldwide citation)

A family of cDNA sequences derived from hepatitis C virus (HCV) are provided. These sequences encode antigens which react immunologically with antibodies present in individuals with non-A non-B hepatitis (NANBH), but which generally are absent from individuals infected with hepatitis A virus (HAV) o ...


4
Houghton Michael, Choo Qui Lim, Kuo George: Nanbv diagnostics and vaccines.. Chiron, September 19, 1990: EP0388232-A1 (204 worldwide citation)

A new virus, Hepatitis C virus (HCV), which has proven to be the major etiologic agent of blood-borne NANBH, was discovered by Applicant. The initial work on this virus, which includes a partial genomic sequence of the prototype HCV isolate, is described in EPO Pub. No. 318,216, and PCT Pub. No. WO/ ...


5
Nakagawa Satochi, Mizoguchi Hiroshi, Ando Seiko, Hayashi Mikiro, Ochiai Keiko, Yokoi Haruhiko, Tateishi Naoko, Senoh Akihiro, Ikeda Masato, Ozaki Akio: Novel polynucleotides. Kyowa Hakko Kogyo, June 20, 2001: EP1108790-A2 (180 worldwide citation)

Novel polynucleotides derived from microorganisms belonging to coryneform bacteria and fragments thereof, polypeptides encoded by the polynucleotides and fragments thereof, polynucleotide arrays comprising the polynucleotides and fragments thereof, recording media in which the nucleotide sequences o ...


6
Robert I Fox, Richard Houghton: Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse. Scripps Clinic and Research Foundation, Dressler Goldsmith Shore Sutker & Milnamow, November 7, 1989: US04879213 (172 worldwide citation)

A synthetic polypeptide that contains about 6 to about 40 amino acid residues that immunologically mimics the early antigen-diffuse (EA-D) protein of the Epstein-Barr virus (EBV) is disclosed, as are receptors raised to that polypeptide, methods of their use and a reagent system. A polypeptide of th ...


7
Christopher H Contag, Pamela R Contag, David A Benaron: Non-invasive localization of a light-emitting conjugate in a mammal. The Board of Trustees of the Leland Stanford Junior University, Pennie & Edmonds, July 22, 1997: US05650135 (153 worldwide citation)

Methods and compositions for detecting and localizing light originating from a mammal are disclosed. Also disclosed are methods for targeting light emission to selected regions, as well as for tracking entities within the mammal. In addition, animal models for disease states are disclosed, as are me ...


8
Yuzhou Wang, Weixin Tang, William J Cronin, Paul A Liberti: Method for magnetic separation featuring magnetic particles in a multi-phase system. Immunivest Corporation, Dann Dorfman Herrell and Skillman, July 30, 1996: US05541072 (146 worldwide citation)

Methods and devices are provided for separation of magnetic particles and/or magnetic-associated substances from non-magnetic associated substances and media. The methods are specifically applicable to biological separation, and utilize a phase phenomenon arising from mutual interactions between sus ...


9
Michael R Imrich, John K Zeis, Steven P Miller, Allan D Pronovost: Lateral flow medical diagnostic assay device with sample extraction means. Quidel Corporation, Townsend and Townsend Khourie and Crew, May 16, 1995: US05415994 (136 worldwide citation)

The present invention provides devices, methods, and kits for treatment and detection of analytes requiring pretreatment in samples. One-step treatment and detection is possible utilizing the devices and methods of the present invention.


10
Scott M Clark: Reversible flow chromatographic binding assay. IDEXX Laboratories, Fish & Richardson P C, March 10, 1998: US05726010 (131 worldwide citation)

Disclosed are devices and methods for performing an assay which determines the presence or quantity of an analyte in a fluid sample by detecting binding of the analyte to at least one immobilized analyte capture reagent and washing unbound material from the immobilized analyte capture reagent. The d ...