1
David A Gough: Transparent multi-oxygen sensor array and method of using same. The Regents of the University of California, Brown Martin Haller & Meador, November 1, 1988: US04781798 (624 worldwide citation)

A transparent electrochemical oxygen sensor for simultaneously determining oxygen concentration at different locations on a biological surface that is capable of being positioned over the region sought to be measured and includes an array of independently functioning oxygen-sensitive electrodes, a c ...


2
David P Newman: Membrane for enzyme electrodes. The Yellow Springs Instrument Company, Biebel French & Nauman, September 7, 1976: US03979274 (530 worldwide citation)

A laminated membrane for use with an enzyme electrode without the need for use of a compensating electrode. The laminated membrane comprises a layer of essentially homogeneous material such as cellulose acetate or silicone rubber which will prevent passage of even low molecular weight interfering ma ...


3
Shiro Nankai, Mariko Kawaguri, Tashi Iijima: Biosensor and method for making the same. Matsushita Electric Industrial, Lowe Price LeBlanc Becker & Shur, January 30, 1990: US04897173 (509 worldwide citation)

This invention relates to a biosensor which comprises an insulative base, an electrode system formed on the substrate and primarily made of carbon, and a perforated body having an enzyme and an electron acceptor and integrally combined with the electrode system whereby a concentration of a specific ...


4
Chung Chiun Liu, Vasilios A Karagounis: Apparatus for electrochemical measurements. Case Western Reserve University, Renner Otto Boisselle & Lyon, February 18, 1986: US04571292 (506 worldwide citation)

A sensor for an electrochemically active species, such as oxygen, uses more than two electrodes, namely, at least a working electrode, counter electrode and reference electrode. The sensor preferably is substantially planar, is made using thick film or thin film technique and accordingly may be very ...


5
John W Parce, Robert F Zuk: Measuring with zero volume cell. Molecular Devices Corporation, Allegretti & Witcoff, March 27, 1990: US04911794 (417 worldwide citation)

Methods and apparatuses are described for determining the presence of an analyte in a sample suspected of containing the analyte. The method comprises contacting a concentrate of a determinable element capable of being detected by means of a semiconductive electrode with the electrode in the presenc ...


6
Frank E Semersky, Barry Watson: Flow-through electrochemical system analytical method. Technicon Instruments Corporation, S P Tedesco, October 30, 1979: US04172770 (416 worldwide citation)

An electrochemical system using a flow-through electrode design employing a dual separation method to lower electrode poisoning due to large chemical species and interference current due to small electroactive species is disclosed. The system includes a fluid inlet to a reaction chamber and a fluid ...


7
Graham Davis, Hugh A O Hill: Assay systems using more than one enzyme. Genetics International, July 19, 1988: US04758323 (396 worldwide citation)

This specification discloses methods of detection or measurement of an enzyme or of its specific substrate, and sensors used in such methods. The present invention is concerned with a multi-enzyme system, and the specification discloses, as one aspect of the invention a method of assay in which an e ...


8
Kawaguri Mariko, Nankai Shiro, Iijima Takashi: Biosensor.. Matsushita Electric, April 10, 1985: EP0136362-A1 (392 worldwide citation)

A measuring electrode (27) and an adjacent electrode (28) are embedded in an insulating substrate (26). The exposed surface of the electrode system is coated with a porous substance (29) carrying an oxidation reductase (30) and, if needed, an electron acceptor (31) in a dry state, to form a biosenso ...


9
Birch Brian Jeffrey, Burns Ian William: Method and apparatus for electrochemical measurements.. Unilever, Unilever, February 3, 1988: EP0255291-A1 (341 worldwide citation)

A method for measurement or detection of a component of an aqueous liquid sample, said method comprising: placing a sample, possibly containing the component to be analysed, into a reaction zone in a reaction cell, said reaction cell comprising at least two electrodes having an impedance which rende ...


10
Stephen J Churchouse: Methods of operating enzyme electrode sensors. Imperial Chemical, Cushman Darby & Cushman, June 19, 1990: US04935105 (318 worldwide citation)

An analytical method using a sensor of the enzyme electrode type is provided for determining in a sample the concentration of an analyte reactive with an enzyme present on the sensor to produce an electrochemically active species detectable by the sensor, which comprises applying a potential across ...