1
David Mosley
Peter A Carr, Brian Y Chow, Joseph M Jacobson, David W Mosley, Christopher Emig: Methods for High Fidelity Production of Long Nucleic Acid Molecules with Error Control. Massachusetts Institute of Technology, January 3, 2013: US20130005612-A1

A method for synthesizing a nucleic acid having a desired sequence and length comprises providing a solid support having an immobilized nucleic acid, performing a nucleic acid addition reaction to elongate the immobilized nucleic acid by adding a nucleotide or an oligonucleotide attached to a protec ...


2
Adam Heller, Benjamin J Feldman, James Say, Mark S Vreeke: Method of using a small volume in vitro analyte sensor. Therasense, Merchant & Gould P C, September 19, 2000: US06120676 (1145 worldwide citation)

A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 .mu.L. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. I ...


3
Adam Heller, Benjamin J Feldman, James Say, Mark S Vreeke: Small volume in vitro analyte sensor. E Heller & Company, Merchant & Gould P C, November 7, 2000: US06143164 (1035 worldwide citation)

A sensor designed to determine the amount and concentration of analyte in a sample having a volume of less than about 1 .mu.L. The sensor has a working electrode coated with a non-leachable redox mediator. The redox mediator acts as an electron transfer agent between the analyte and the electrode. I ...


4
Brian A Gregg, Adam Heller, Wolfgang Kerner, Michael V Pishko, Ioanis Katakis: Enzyme electrodes. Pravel Hewitt Kimball & Krieger, November 23, 1993: US05264104 (997 worldwide citation)

An improved enzyme electrode includes a three-dimensional redox polymer network having redox enzymes bound thereto, and also having a protein excluding polymeric coating.


5
Nigel F Carter, Geoffrey R Chambers, Graham J Hughes, Steven Scott, Gurdial S Sanghera, Jared L Watkin: Electrochemical sensor. MediSense, Fish & Richardson P C, May 13, 1997: US05628890 (958 worldwide citation)

An electrode strip for use in an electrochemical sensor for measuring a compound in a sample is provided, including an electrode support, a reference or counter electrode disposed on the support, a working electrode spaced from the reference or counter electrode on the support, a covering layer defi ...


6
Adam Heller, Ruben Maidan: Interferant eliminating biosensors. E Heller & Company, Pravel Hewitt Kimball & Krieger, November 16, 1993: US05262305 (824 worldwide citation)

A biosensor including an interferant-eliminating catalyst and method for analyzing an analyte in a biological sample is disclosed.


7
Shiro Nankai, Mariko Kawaguri, Toshihiko Yoshioka, Haruhiro Tsutsumi, Kyozo Terao, Naoki Tanimoto, Masahiro Yoshioka, Hiroshi Hyodo, Takatoshi Uchigaki: Quantitative analysis method and its system using a disposable sensor. Matsushita Electric Industrial, Kyoto Daiichi Kagaku, November 30, 1993: US05266179 (788 worldwide citation)

A sensor 13 is inserted into a connector 14. A constant voltage required to obtain a response current is applied across the connector 14 by a voltage applying source 15 at timings required. A response current of the sensor 13 inserted into the connector 14 is converted into a voltage by a current-to ...


8
Shiro Nankai, Mariko Kawaguri, Mayumi Ohtani, Takashi Iijima: Biosensor and a process for preparation thereof. Matsushita Electric Industrial, Stevens Davis Miller & Mosher, June 9, 1992: US05120420 (759 worldwide citation)

A biosensor of the invention comprises an insulating base board (1) having formed thereon, in sequence, leads (2, 3, 3'), an electrode system mainly made of carbon (4, 5, 5'), an insulating layer (6) and a reaction layer (14) composed of an enzyme and an electron acceptor, and being provided thereon ...


9
W Kenneth Ward, Eric S Wilgus: Device for monitoring changes in analyte concentration. Kolisch Hartwell Dickinson McCormack & Heuser, January 27, 1998: US05711861 (758 worldwide citation)

The invention provides an electrochemical sensor system for measuring analyte concentrations in a sample fluid. The invention is particularly useful for measuring analytes such as glucose in a patient. An implantable glucose sensor includes a disc-shaped body containing multiple anodes on opposing s ...


10
Kirk W Johnson, John J Mastrototaro: Techniques to improve the performance of electrochemical sensors. Eli Lilly and Company, Woodard Emhardt Naughton Moriarty & McNett, May 2, 1995: US05411647 (744 worldwide citation)

A method of improving the utility of electrochemical glucose sensors by decreasing either or both their settling time and their sensitivity to interfering compounds. In particular, the settling time of an electrochemical glucose sensor is improved by pretreating the operating electrode with a negati ...