1
Alec Mian, Stephen G Kieffer Higgins, George D Corey: Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system. Silicon Valley Bank, November 20, 2001: US06319469 (242 worldwide citation)

This invention relates to methods and apparatus for performing microanalytic and microsynthetic analysis and procedures. The invention provides a microsystem platform and a micromanipulation device for manipulating the platform that utilizes the centripetal force resulting from rotation of the platf ...


2
Gerald W Callan, William D Corry, Richard E Scordato, John G Gorman: Agglutination detection apparatus. Medical Laboratory Automation, Wolf Greenfield & Sacks, October 26, 1993: US05256376 (114 worldwide citation)

A method and apparatus are provided for use with a centrifuge to analyze reactants. The apparatus includes at least one cuvette having at least one chamber. The chamber has a radially outward wall which provides a base upon which reactants can be pelleted when the device is rotated about a centrifug ...


3
Willie W Jordan: Reagent pack and carousel. Abbott Laboratories, Roberta L Hastreiter, Clifford A Dean, July 18, 1989: US04849177 (100 worldwide citation)

A multiple dose reagent pack and corresponding carousel for an automated analyzer are disclosed. The reagent pack contains a plurality of vial-receiving wells which receive and hold a plurality of reagent-containing vials to form a unitary reagent pack. The carousel contains a plurality of radially ...


4
Cottingham Hugh V: Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay. Becton Dickinson Co, January 24, 1996: EP0693560-A2 (98 worldwide citation)

A disposable, self-contained test unit is provided for use in carrying out an immunoassay or an integrated nucleic acid amplification and nucleic acid assay. The test unit includes sample, reagent and waste chambers, and the flow of sample and reagent liquids is controlled by centrifugal force. Diff ...


5
Anderson Norman G: Multistation, single channel analytical photometer and method of use. N A, January 12, 1971: US3555284 (93 worldwide citation)

An analytical photometer is provided for simultaneously determining the presence of a common substance in a multiplicity of discrete samples. A multiplicity of sample chambers with axially aligned transparent windows are arranged within a centrifuge rotor to provide a rotary cuvette system. Solution ...


6
Sigmar Klose, Fritz Stahler, Hans Lange, Wolfgang Kleemann: Method for carrying out analytical determinations. Boehringer Mannheim, Felfe & Lynch, May 7, 1985: US04515889 (90 worldwide citation)

The present invention provides a process for carrying out analytical determinations by mixing and incubating a sample solution with at least one reagent and optically measuring a parameter in the incubated reaction mixture. The mixing, incubating and measuring are carried out during the action of a ...


7
Marlo R Andersen, Thomas O Tiffany, Mario J Gangitano: Liquid handling. Fisher Scientific Company, August 2, 1988: US04761268 (89 worldwide citation)

A liquid handling system that is particularly useful in a clinical analysis system includes a cuvette loading station for receiving a centrifugal analyzer rotor with two compartment cuvettes. Fixedly mounted on transfer structure are two spaced apart liquid handling probes such that the two probes m ...


8
Boris Braynin, Tammy L Burd, Vladimir Ostoich: Apparatus and method for optically analyzing biological fluids. Abaxis, Townsend and Townsend, June 16, 1992: US05122284 (88 worldwide citation)

A centrifugal rotor comprising a plurality of peripheral cuvettes and a collection chamber spaced radially inward from the cuvettes is disclosed. The rotor includes a means for introducing fluid into the collection chamber and plurality of generally radial inlet channels connecting each cuvette to t ...


9
Douglas E Boyd, Jan B Yates, Ronald K Coleman: Electrochemical analytical cartridge. Careside, Oppenheimer Wolff & Donnelly, June 29, 1999: US05916522 (83 worldwide citation)

An electro-analytical cartridge adapted for use in analyzing fluids. The cartridge includes an electrochemical device that measures ionic activity using ion-specific electrodes. The cartridge further includes a plumbing system composed of the electrochemical device and various wells or chambers whic ...


10
Anderson Norman G, Burtis Carl A, Johnson Wayne F, Mailen James C, Scott Charles D: Compact dynamic multistation photometer utilizing disposable cuvette rotor. The United States of America represented by the United States Atomic, Horan John A, March 19, 1974: US3798459 (82 worldwide citation)

A compact analytical photometer of the rotary cuvette type designed to use small disposable cuvette rotors. A power driven cuvette rotor holder having a generally flat, circular configuration is provided with an integral, upstanding, annular lip for receiving, in an easily insertable and removable f ...