1
Joseph Gross, John Gerard Kelly: Analyte-controlled liquid delivery device and analyte monitor. Elan Medical Technologies, Kathleen L Maher, September 1, 1998: US05800420 (920 worldwide citation)

A liquid delivery device comprising a housing having a lower surface for application to the skin of a subject and having a reservoir and a gas generation chamber therein separated by a displaceable membrane. Gas generated by an electrolytic cell under the control of a microprocessor causes the gas g ...


2
Joseph Gross, John Gerard Kelly: Analyte-controlled liquid delivery device and analyte monitor. Elan Medical Technologies, Kathleen L Maher, October 13, 1998: US05820622 (540 worldwide citation)

A liquid delivery device comprising a housing having a lower surface for application to the skin of a subject and having a reservoir and a gas generation chamber therein separated by a displaceable membrane. Gas generated by an electrolytic cell under the control of a microprocessor causes the gas g ...


3
Peter Wilding, Larry J Kricka: Mesoscale sample preparation device and systems for determination and processing of analytes. Trustees of the University of Pennsylvania, Dann Dorfman Herrell and Skillman, March 10, 1998: US05726026 (398 worldwide citation)

A mesoscale sample preparation device capable of providing microvolume test samples, separated into a cell-enriched fraction and a fraction of reduced cell content, for performing various analyses, such as binding assays, determinations involving polynucleotide amplification and the like. Analytical ...


4
Elizabeth A Holmes, Shaunak Roy, John Howard, Chengwang Wang: Medical device for analyte monitoring and drug delivery. Theranos, Wilson Sonsini Goodrich & Rosati, November 6, 2007: US07291497 (273 worldwide citation)

The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and is capable of releasing the therape ...


5
Timothy W Woudenberg, Michael Albin, Reid B Kowallis, Yefim Raysberg, Robert P Ragusa, Emily S Winn Deen: Device for multiple analyte detection. The Perkins Elmer Corporation, Vincent M Powers, October 3, 2000: US06126899 (254 worldwide citation)

The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid ...


6
Daniel Pinkel, Joe Gray: High density array fabrication and readout method for a fiber optic biosensor. The Regents of the University of California, Townsend and Townsend and Crew, November 25, 1997: US05690894 (243 worldwide citation)

The invention relates to the fabrication and use of biosensors comprising a plurality of optical fibers each fiber having attached to its "sensor end" biological "binding partners" (molecules that specifically bind other molecules to form a binding complex such as antibody-antigen, lectin-carbohydra ...


7
Jorma Virtanen: Laboratory in a disk. Burstein Laboratories, Albert P Halluin, J David Howrey & Simon Smith, February 29, 2000: US06030581 (230 worldwide citation)

An apparatus is described that includes an optical disk, adapted to be read by an optical reader, comprising a first sector having substantially self-contained assay means for localizing an analyte suspected of being in a sample to at least one, predetermined location in the first sector and a secon ...


8
Frederick Vachss: Optical detector for windshield wiper control. Rockwell International Corporation, John C McFarren, May 17, 1994: US05313072 (218 worldwide citation)

An optical device is provided for detecting the degree of obscuring moisture or precipitation on the windshield of an automotive vehicle. A source of light, such as a light emitting diode (LED) or a laser diode, is positioned to illuminate the windshield. An optical imager and detector array senses ...


9
Peter John Zanzucchi, Satyam Choudary Cherukuri, Sterling Edward McBride: Partitioned microelectronic device array. David Sarnoff Research Center, William J Burke, May 26, 1998: US05755942 (216 worldwide citation)

A system for processing a plurality of tests or syntheses in parallel comprising a sample channel for moving samples into a microlaboratory array of a plurality of wells connected by one or more channels for the testing or synthesis of samples, a station for housing the array and an optical system c ...


10
George M Church: Replica amplification of nucleic acid arrays. President and Fellows of Harvard College, Banner & Witcoff, August 13, 2002: US06432360 (211 worldwide citation)

A method of producing a plurality of a nucleic acid array, comprising, in order, the steps of amplifying in situ nucleic acid molecules of a first randomly-patterned, immobilized nucleic acid array comprising a heterogeneous pool of nucleic acid molecules affixed to a support, transferring at least ...