1
David Mosley
Peter A Carr, Brian Y Chow, Joseph M Jacobson, David W Mosley, Christopher Emig: Methods for high fidelity production of long nucleic acid molecules. Massachusetts Institute of Technology, Norma E Henderson, February 1, 2011: US07879580 (18 worldwide citation)

This invention generally relates to nucleic acid synthesis, in particular DNA synthesis. More particularly, the invention relates to the production of long nucleic acid molecules with precise user control over sequence content. This invention also relates to the prevention and/or removal of errors w ...


2
David Mosley
Peter A Carr, Brian Y Chow, Joseph M Jacobson, David W Mosley, Christopher Emig: Methods for high fidelity production of long nucleic acid molecules with error control. Massachusetts Institute of Technology, Norma E Henderson, April 26, 2011: US07932025 (13 worldwide citation)

This invention generally relates to nucleic acid synthesis, in particular DNA synthesis. More particularly, the invention relates to the production of long nucleic acid molecules with precise user control over sequence content. This invention also relates to the prevention and/or removal of errors w ...


3
David Mosley
Peter A Carr, Brian Y Chow, Joseph M Jacobson, David W Mosley, Christopher Emig: Methods for high fidelity production of long nucleic acid molecules with error control. Massachusetts Institute of Technology, Norma E Henderson, September 11, 2012: US08263335 (10 worldwide citation)

A method for synthesizing a nucleic acid having a desired sequence and length comprises providing a solid support having an immobilized nucleic acid, performing a nucleic acid addition reaction to elongate the immobilized nucleic acid by adding a nucleotide or an oligonucleotide to the nucleic acid, ...


4
David Mosley
Peter A Carr, Brian Y Chow, Joseph M Jacobson, David W Mosley, Christopher Emig: Methods for high fidelity production of long nucleic acid molecules. Massachusetts Institute of Technology, Norma E Henderson, June 26, 2012: US08206952 (10 worldwide citation)

In a method for synthesizing a long nucleic acid molecule, a first immobilized nucleic acid has a first 5′ region and a first 3′ region and a second immobilized nucleic acid has a second 5′ region and a second 3′ region. The second 3′ region and the first 5′ region have identical nucleic acid sequen ...


5
David Mosley
Peter A Carr, Brian Y Chow, Joseph M Jacobson, David W Mosley, Christopher Emig: Methods for high fidelity production of long nucleic acid molecules. Massachusetts Institute of Technology, Norma E Henderson, August 13, 2013: US08507226 (9 worldwide citation)

In a method for synthesizing a pool of nucleic acid molecules, a first nucleic acid has a first 5′ region and a first 3′ region and a second nucleic acid has a second 5′ region and a second 3′ region. The second 3′ region and the first 5′ region have identical nucleic acid sequences. The first 3′ re ...


6
Kary B Mullis, Henry A Erlich, Norman Arnheim, Glenn T Horn, Randall K Saiki, Stephen J Scharf: Process for amplifying, detecting, and/or-cloning nucleic acid sequences. Cetus Corporation, Janet E Hasak, Albert P Halluin, July 28, 1987: US04683195 (3575 worldwide citation)

The present invention is directed to a process for amplifying and detecting any target nucleic acid sequence contained in a nucleic acid or mixture thereof. The process comprises treating separate complementary strands of the nucleic acid with a molar excess of two oligonucleotide primers, extending ...


7
Kary B Mullis, Henry A Erlich, David H Gelfand, Glenn Horn, Randall K Saiki: Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme. Cetus Corporation, Kevin R Kaster, Janet E Hasak, Albert P Halloin, October 23, 1990: US04965188 (1379 worldwide citation)

A process for amplifying any target nucleic acid sequence contained in a nucleic acid or mixture thereof comprises treating separate complementary strands of the nucleic acid with a molar excess of two oligonucleotide primers and extending the primers with a thermostable enzyme to form complementary ...


8
Andrew Fire, Stephen Kostas, Mary Montgomery, Lisa Timmons, SiQun Xu, Hiroaki Tabara, Samuel E Driver, Craig C Mello: Genetic inhibition by double-stranded RNA. Carnegie Institute of Washington, Morgan Lewis & Bockius, January 14, 2003: US06506559 (958 worldwide citation)

A process is provided of introducing an RNA into a living cell to inhibit gene expression of a target gene in that cell. The process may be practiced ex vivo or in vivo. The RNA has a region with double-stranded structure. Inhibition is sequence-specific in that the nucleotide sequences of the duple ...


9
Marianne Malven, Jennifer Rinehart, Nancy Taylor, Ellen Dickinson: Soybean event MON89788 and methods for detection thereof. Monsanto Technology, SNR Denton US, Pamela J Sisson Esq, November 8, 2011: US08053184 (943 worldwide citation)

The present invention provides for soybean plant and seed comprising transformation event MON89788 and DNA molecules unique to these events. The invention also provides methods for detecting the presence of these DNA molecules in a sample.


10
Richard Axel, Michael H Wigler, Saul J Silverstein: Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials. The Trustees of Columbia University, John P White, August 16, 1983: US04399216 (700 worldwide citation)

The present invention relates to processes for inserting DNA into eucaryotic cells, particularly DNA which includes a gene or genes coding for desired proteinaceous materials for which no selective criteria exist. The insertion of such DNA molecules is accomplished by cotransforming eucaryotic cells ...