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Tarran Jones
Goldstein Neil I, Giorgio Nicholas A, Jones Steven Tarran, Saldanha Jose William: Antibody and antibody fragments for inhibiting the growth of tumors. Imclone Systems, April 1, 1998: EP0831880-A1

Chimerized and humanized versions of anti EGF receptor antibody 225 and fragments thereof for treatment of tumors.


2
Cabilly Shmuel, Holmes William Evans, Wetzel Ronald Burnell, Heyneker Herbert Louis, Riggs Arthur Dale: Recombinant immunoglobulin preparations, methods for their preparation, dna sequences, expression vectors and recombinant host cells therefor.. Genentech, Hope City, November 14, 1984: EP0125023-A1 (375 worldwide citation)

Recombinant DNA techniques are used to produce both immunoglobulins which are analogous to those normally found in vertebrate systems and to take advantage of these gene modification techniques to construct chimeric or other modified forms.


3
Boss Michael Alan, Kenten John Henry, Emtage John Spencer, Wood Clive Ross: Processes for the production of multichain polypeptides or proteins.. Celltech, October 3, 1984: EP0120694-A2 (272 worldwide citation)

This invention relates to multichain polypeptides or proteins and processes for their production in cells of host organisms which have been transformed by recombinant DNA techniques. According to a first aspect of the present invention, there is provided a process for producing a heterologous multic ...


4
Kunsch Charles A, Choi Gil H, Barash Steven C, Dillon Patrick J, Fannon Michael R, Rosen Craig A: Staphylococcus aureus polynucleotides and sequences. Human Genome Sciences, July 30, 1997: EP0786519-A2 (232 worldwide citation)

The present invention provides polynucleotide sequences of the genome of Staphylococcus aureus, polypeptide sequences encoded by the polynucleotide sequences, corresponding polynucleotides and polypeptides, vectors and hosts comprising the polynucleotides, and assays and other uses thereof. The pres ...


5
Houghton Michael, Choo Qui Lim, Kuo George: Nanbv diagnostics and vaccines.. Chiron, May 31, 1989: EP0318216-A1 (229 worldwide citation)

A family of cDNA sequences derived from hepatitis C virus (HCV) are provided. These sequences encode antigens which react immunologically with antibodies present in individuals with non-A non-B hepatitis (NANBH), but which generally are absent from individuals infected with hepatitis A virus (HAV) o ...


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Bott Richard Ray, Ferrari Eugenio, Wells James Allen, Estell David Aaron, Henner Dennis James: Procaryotic carbonyl hydrolases, methods, dna, vectors and transformed hosts for producing them, and detergent compositions containing them.. Genentech, January 9, 1985: EP0130756-A1 (186 worldwide citation)

Methods and vectors are provided for the production of procaryotic carbonyl hydrolases in recombinant systems. DNA which encodes such hydrolases are mutated at predetermined regions by known methods or by a novel point mutagenesis method in order to generate mutant hydrolases. Particular point mutat ...


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Nakagawa Satochi, Mizoguchi Hiroshi, Ando Seiko, Hayashi Mikiro, Ochiai Keiko, Yokoi Haruhiko, Tateishi Naoko, Senoh Akihiro, Ikeda Masato, Ozaki Akio: Novel polynucleotides. Kyowa Hakko Kogyo, June 20, 2001: EP1108790-A2 (180 worldwide citation)

Novel polynucleotides derived from microorganisms belonging to coryneform bacteria and fragments thereof, polypeptides encoded by the polynucleotides and fragments thereof, polynucleotide arrays comprising the polynucleotides and fragments thereof, recording media in which the nucleotide sequences o ...


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Queen Cary L, Selick Harold Edwin: Chimeric immunoglobulins specific for p55 tac protein of the il-2 receptor.. Protein Design Labs, October 16, 1991: EP0451216-A1 (150 worldwide citation)

Novel methods for designing humanized immunoglobulins having one or more complementary determining regions (CDR's) from a donor immunoglobulin and a framework region from a human immunoglobulin comprising first comparing the framework or variable region amino acid sequence of the donor immunoglobuli ...


10
Dumas Milne Edwards Jean Bapti, Duclert Aymeric, Giordano Jean Yves: Expressed sequence tags and encoded human proteins. Genset, September 6, 2000: EP1033401-A2 (135 worldwide citation)

The sequences of 5' ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5' ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5' ESTs. The 5' ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. Upstream regulatory sequences ...



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