Ernst B Hunziker: Method and compositions for the treatment and repair of defects or lesions in cartilage. Robert F Shaw, James F Haley Jr, Jane A Massaro, April 27, 1993: US05206023 (358 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects or lesions in the cartilage of humans and other animals. The defect or lesion in the cartilage may be first treated with an enzyme to remove proteoglycans from the defect area. To induce cartilage formation, the defect is ...

Ernst B Hunziker: Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone. Robert Francis Shaw, Edward F Mullowney, Jane A Massaro, December 14, 1993: US05270300 (280 worldwide citation)

Methods and compositions are provided for the treatment and repair of defects in the cartilage or bone of humans and other animals as in full-thickness defects in joints. The defect in bone is filled with a matrix having pores large enough to allow cells to populate the matrix and to form blood vess ...


Fritz Wittwer, Ivan Tomka: Polymer composition for injection molding. Warner Lambert Company, Howard Olevsky, Stephen Raines, June 16, 1987: US04673438 (181 worldwide citation)

Capsules and other shaped products formed from a moldable starch composition in an injection molding device is disclosed in the present invention. The composition comprising starch having a molecular mass range of 10,000 to 20,000,000 Dalton, and a water content range from 5 to 30% by weight. The st ...

Marshall R Urist: Bone morphogenetic agents. The Regents of the University of California, Kenyon & Kenyon, January 3, 1989: US04795804 (118 worldwide citation)

The production and isolation of bone morphogenetic peptide agents displaying the osteoinductive and immunoreactive activity of bone morphogenetic protein (BMP) and deriving from natural, synthetic or recombinant DNA sources, and said agents.

Ivan Tomka: Thermoplastically processable starch and a method of making it. Ostrolenk Faber Gerb & Soffen, November 8, 1994: US05362777 (99 worldwide citation)

In order to produce thermoplastically processable starch, an additive or plasticizer respectively is mixed with native or natural starch and the mixture is caused to melt by the application of heat and mechanical energy. The additive is a substance which lowers the melting point of the starch so tha ...

Mark D Lauren: Novel biomaterial of cross-linked peritoneal tissue. Bacon & Thomas, July 5, 1988: US04755593 (94 worldwide citation)

A biomaterial suitable for use in medical devices which comprises peritoneal tissue, especially animal parietal peritoneum tissue, which has been chemically treated to crosslink the collagen in the tissue.

Robert C Chang, Kari I Kivirikko, Thomas B Neff, David R Olsen, James W Polarek: Recombinant gelatins. FibroGen, James E Nesbitt, Leanne C Price, FibroGen, January 31, 2006: US06992172 (84 worldwide citation)

The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.

Robert F T Stepto, Ivan Tomka, Beat Dobler, Keith Pyrah: Destructurized starch and method for making same. Warner Lambert Company, Fitzpatrick Cella Harper & Scinto, January 17, 1995: US05382611 (59 worldwide citation)

A destructurized native starch material is described which has a water content in the range of about 10 to 25% by weight and that its mass average molar mass is reduced by a factor of 2 to 5000 compared to its original mass average molar mass. The destructurized starch is produced by heating a chemi ...

Fritz Wittwer, Ivan Tomka: Method of conditioning a water swellable hydrocolloid. Warner Lambert Company, Louis S Gillow, November 13, 1984: US04482386 (57 worldwide citation)

Method to condition water-swellable hydrocolloids for use in mechanical forming processes such as die molding or injection molding. To avoid long conditioning times at high temperature, the hydrocolloids are conditioned to the predetermined water content at ambient temperature and then rapidly heate ...