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Tarran Jones
Masayuki Tsuchiya, Koh Sato, Mary Margaret Bendig, Steven Tarran Jones, Jose William Saldanha: Reshaped human antibody to human interleukin-6 receptor. Chugai Seiyaku Kabushiki Kaisha, Foley & Lardner, January 20, 2009: US07479543 (96 worldwide citation)

A reshaped human antibody to the human IL-6R, comprising: (A) an L chain comprising, (1) a human L chain C region, and (2) an L chain V region comprising human L chain framework regions (FRs), and mouse L chain complementary determination regions (CDRs) of a momoclonal antibody to the IL-6 receptor ...


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Tarran Jones
Gregory J LaRosa, Christopher Horvath, Walter Newman, S Tarran Jones, Siobhan H O&apos Brien, Theresa O&apos Keefe: Humanized anti-CCR2 antibodies and methods of use therefor. Millennium Pharmaceuticals, Hamilton Brook Smith & Reynolds P C, February 24, 2004: US06696550 (40 worldwide citation)

The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the intera ...


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Tarran Jones
Gregory J LaRosa, Christopher Horvath, Walter Newman, S Tarran Jones, Siobhan H O&apos Brien, Theresa O&apos Keefe: Recombinant anti-CCR2 antibodies and methods of use therefor. Millennium Pharmaceuticals, Hamilton Brook Smith & Reynolds P C, April 27, 2004: US06727349 (29 worldwide citation)

The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the intera ...


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Tarran Jones
Britta Hardy, Steven Tarran Jones, Leah Klapper: Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency. CureTech, Mor Research Applications, Winston & Strawn, February 19, 2008: US07332582 (21 worldwide citation)

The present invention provides to a humanized monoclonal antibody having immunostimulatory effects. This antibody binds specifically to B lymphoblastoid cells, induces proliferation and activation of peripheral blood lymphocytes, and is capable of eliciting an anti-tumor effect upon administration t ...


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Tarran Jones
Britta Hardy, Steven Tarran Jones, Leah Klapper: Humanized immunomodulatory monoclonal antibodies for the treatment of immunodeficiency. CureTech, Mor Research Applications, Winston & Strawn, July 19, 2011: US07981416 (9 worldwide citation)

The present invention provides to a humanized monoclonal antibody having immunostimulatory effects. This antibody binds specifically to B lymphoblastoid cells, induces proliferation and activation of peripheral blood lymphocytes, particularly T cells, and is capable of eliciting an anti-tumor effect ...


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Tarran Jones
Britta Hardy, Steven Tarran Jones, Leah Klapper: Human immunomodulatory monoclonal antibodies for the treatment of cancer. CureTech, Mor Research Application, Winston & Strawn, April 28, 2009: US07524498 (7 worldwide citation)

The present invention provides to a humanized monoclonal antibody having immunostimulatory effects. This antibody binds specifically to B lymphoblastoid cells, induces proliferation and activation of peripheral blood lymphocytes, particularly T cells, and is capable of eliciting an anti-tumor effect ...


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Tarran Jones
Roger A Sabbadini, William A Garland, Genevieve Hansen, Steven Tarran Jones, David Gareth Williams: Compositions and methods for binding sphingosine-1-phosphate. Lpath, BioTechnology Law Group, Daniel M Chambers, November 9, 2010: US07829674 (4 worldwide citation)

The present invention relates to anti-S1P agents, for example, humanized monoclonal antibodies, and their uses for detection of S1P or for treatment of diseases and conditions associated with S1P.


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Tarran Jones
Gregory J LaRosa, Christopher Horvath, Walter Newman, S Tarran Jones, Siobhan H O Brien, Theresa O Keefe: Humanized anti-CCR2 antibodies and methods of use therefor. Millennium Pharmaceuticals, Lowrie Lando & Anastasi, January 6, 2009: US07473421 (4 worldwide citation)

The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the intera ...


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Tarran Jones
Gregory J LaRosa, Christopher Horvath, Walter Newman, S Tarran Jones, Siobhan H O Brien, Theresa O Keefe: Humanized anti-CCR2 antibodies and methods of use therefor. Millennium Pharmaceuticals, Lando & Anastasi, July 24, 2012: US08227211 (3 worldwide citation)

The present invention relates to a humanized antibody or functional fragment thereof which binds to a mammalian (e.g., human) CC-chemokine receptor 2 (CCR2) or a portion of the receptor and blocks binding of a ligand to the receptor. The invention further relates to a method of inhibiting the intera ...