1

2
James Doherty
Dorn Conrad P, Finke Paul E, Maccoss Malcolm, Doherty James B, Shah Shrenik K, Hagmann William K: New substituted azetidinones as anti-inflammatory and antidegenerative agents.. Merck & Co, April 22, 1992: EP0481671-A1 (40 worldwide citation)

New substituted azetidinones of the general formula (A') which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents are described. e


3
Stéphane De Lombaert
Rajagopal Bakthavatchalam, Charles A Blum, Harry Brielmann, Timothy M Caldwell, Stéphane De Lombaert, Kevin J Hodgetts, Xiaozhang Zheng, Taeyoung Yoon: Substituted quinazolin-4-ylamine analogues. Neurogen Corporation, Edwards Angell Palmer & Dodge, Peter F Corless, Mark D Russett, December 4, 2007: US07304059 (3 worldwide citation)

Substituted quinazolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated compani ...


4
Sarah Reybuck Collier
Paul G Rasmussen, Sarah E Reybuck, David M Johnson, Richard G Lawton: Cylic imidazole compounds having relatively low hydrogen content and relatively high nitrogen content and polymers formed therefrom. The Regents of the University of Michigan, Young & Basile, August 1, 2000: US06096899 (3 worldwide citation)

In one embodiment, the invention provides a polymer comprising imidazole ring units having nitrogen at the 1 and 3 positions of the ring; a carbon at each of the 2, 4 and 5 positions of the ring; and radical substituents G1 and G2 carried at the 4 and 5 positions. G1 and G2 are each independently se ...


5
Andreas G Weichert
Andreas Weichert, Hans Jochen Lang, Heinz Werner Kleemann, Jan Robert Schwark, Wolfgang Scholz, Udo Albus: Ortho-substituted benzoylguanidines, including composition and methods of using them. Hoeschst Aktiengesellschaft, Finnegan Henderson Farabow Garrett & Dunner L, October 12, 1999: US05965744 (3 worldwide citation)

The present invention relates to ortho-substituted benzoylguanidines of the formula I, defined in the specification. The invention also embraces processes for making these compounds, as well as compositions and methods of using them. The compounds of the invention exhibit very good antiarrhythmic pr ...


6
Prabhu Mohapatra
Laxminarayan Bhat, Prabhu Prasad Mohapatra, Kouacou Adiey: Methods of utilizing arylpiperazine derivatives. Reviva Pharmaceuticals, Perkins Coie, Viola T Kung, October 14, 2014: US08859552

The present invention provides arylpiperazine derivatives which can be advantageously used for treating schizophrenia and related psychoses such as acute manic, bipolar disorder, autistic disorder, and depression.


7
Barker Andrew John: Quinazoline derivatives.. Zeneca, October 20, 1993: EP0566226-A1 (278 worldwide citation)

The invention concerns quinazoline derivatives of the formula I wherein m is 1, 2 or 3 and each R includes hydroxy, amino, carboxy, carbamoyl, ureido, (1-4C)alkoxycarbonyl, N-(1-4C)alkylcarbamoyl, N,N-di-[(1-4C)alkyl]carbamoyl, hydroxyamino, (1-4C)alkoxyamino, (2-4C)alkanoyloxyamino, trifluoromethox ...


8
Miguel Angel Ondetti, David W Cushman: Proline derivatives and related compounds. E R Squibb & Sons, Lawrence S Levinson, Merle J Smith, August 8, 1978: US04105776 (234 worldwide citation)

New proline derivatives and related compounds which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.


9

10
Moeckli Peter Dr: Cationic iminazoleazodyestuffs. Ciba-Geigy, June 5, 1996: EP0714954-A2 (209 worldwide citation)

Cpds. (I) of formulae (A-NR1-Z-NR2)n-X (IA), A-NR1-Z1-N=N-KK (IB) and A-NR1-Z2-NR2-A1 (IC); and cpds. of formula A-NR1-Z-NR2-H (II), all of which contain 4-(imidazolium-2-azo)-phenyl gp(s)., are claimed. In the formulae, A and A1 = are each a 4-(imidazolium-2-azo)-phenyl gp. of formula (III); Z is a ...