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Prabhu Mohapatra
Laxminarayan Bhat, Prabhu Prasad Mohapatra, Kouacou Adiey: Methods of utilizing arylpiperazine derivatives. Reviva Pharmaceuticals, Perkins Coie, Viola T Kung, October 14, 2014: US08859552

The present invention provides arylpiperazine derivatives which can be advantageously used for treating schizophrenia and related psychoses such as acute manic, bipolar disorder, autistic disorder, and depression.


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Carini David John, Duncia John Jonas Vytautas: Angiotensin ii receptor blocking imidazoles.. Du Pont, January 20, 1988: EP0253310-A2 (316 worldwide citation)

Substituted imidazoles such as are useful as angiotensin II blockers. These compounds have activity in treating hypertension and congestive heart failure.


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Carini David John, Wong Pancras Chor Bun, Duncia John Jonas Vytautas: Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids.. Du Pont, July 19, 1989: EP0324377-A2 (169 worldwide citation)

The invention encompasses a pharmaceutical composition comprising a diuretic or a non-steroidal antiinflammatory drug, a pharmaceutical suitable carrier and an antihypertensive and processes for production of these compositions.


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Peng Cho Tang, Li Sun, Gerald McMahon: 3-heteroaryl-2-indolinone compounds for the treatment of disease. Sugen, Lyon & Lyon, August 11, 1998: US05792783 (164 worldwide citation)

The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.


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David J Carini, John J V Duncia, Pancras C B Wong: Angiotensin II receptor blocking imidazoles. E I Du Pont de Nemours and Company, August 11, 1992: US05138069 (108 worldwide citation)

Substituted imidazoles such as ##STR1## are useful as angiotensin II blockers. These compounds have activity in treating hypertension and congestive heart failure.


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Ravi V J Chari, Viktor S Goldmakher, Walter A Blattler: Cyclopropylbenzindole-containing cytotoxic drugs. Immunogen, Sughrue Mion Zinn Macpeak & Seas, December 17, 1996: US05585499 (103 worldwide citation)

Novel cytotoxic agents comprising a cell binding agent chemically linked to one or more analogue or derivative of CC-1065 are described. The therapeutic use of the cytotoxic agents is also described. These cytotoxic agents have therapeutic use because they deliver the cytotoxic drugs to a specific c ...


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Philip L Southwick, Alan S Waggoner: Intermediate for and fluorescent cyanine dyes containing carboxylic acid groups. Carnegie Mellon University, Cohen & Grigsby, January 1, 1991: US04981977 (99 worldwide citation)

(2,3,3-Trimethyl-3-H-indol-5-yl)-acetic acid has been synthesized. Additionally, derivatives of (2,3,3-Trimethyl-3-H-indol-5-yl)-acetic acid have been prepared as intermediates for preparation of fluorescent cyanine biolabels. A derived dye, 5.5'-Dicarboxymethyl-3,3,3',3'-tetramethyl-1,1'-diethylind ...


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K Barry Sharpless, Valery Fokin, Vsevold A Rostovtsev, Luke Green, Fahmi Himo: Copper-catalysed ligation of azides and acetylenes. The Scripps Research Institute, Donald G Lewis, Talivaldis Cepuritis, Thomas Fitting, May 20, 2008: US07375234 (88 worldwide citation)

A metal catalyzed click chemistry ligation process is employed to bind azides and terminal acetylenes to give triazoles. In many instances, the reaction sequence regiospecifically ligates azides and terminal acetylenes to give only 1,4-disubstituted [1,2,3]-triazoles.