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Tamaki Kazuhiko, Yamaguchi Takahiro, Oda Kozo, Terasaka Naoki, Nakai Daisuke, Nakadai Masakazu: (Ja) 2以上の置換基を有するベンゼン化合物, (En) Benzene compound having 2 or more substituents. Daiichi Sankyo Company, Tamaki Kazuhiko, Yamaguchi Takahiro, Oda Kozo, Terasaka Naoki, Nakai Daisuke, Nakadai Masakazu, YAGUCHI Toshiaki, May 4, 2006: WO/2006/046593 (45 worldwide citation)

(EN) Disclosed is an excellent LXR modulator. Specifically disclosed is a compound represented by the general formula (I) below or the like. (I) [In the formula, R1 represents a -COR9 (wherein R9 represents an alkyl, optionally substituted alkoxy or optionally substituted amino); R2 represents an H, ...


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Helen T Lee, Joseph A Picard, Drago R Sliskovic: .beta.-carboxy sulfonamide ACAT inhibitors. Warner Lambert Company, Charles W Ashbrook, February 13, 1996: US05491170 (7 worldwide citation)

.beta.-Carboxy sulfonyl compounds of the formula ##STR1## wherein R.sub.1 is aryl, R.sub.3 is hydrogen or alkyl, R.sub.3 and R.sub.4 are hydrogen or alkyl, Y is --O--, --S--, or --NR.sub.2 --, and R.sub.5 is alkyl or aryl are potent inhibitors of the enzyme acyl CoA:cholesterol acyltransferase (ACAT ...


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Koenraad Lodewijk August Van Acker, Piet Tom Bert Paul Wigerinck, Lieve Emma Jan Michiels, Abdellah Tahri: Entry inhibitors of the HIV virus. Janssen R&D Ireland, Toni Junell Herbert, September 18, 2012: US08268885 (1 worldwide citation)

The present invention relates to small molecules as entry inhibitors of the HIV virus, processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present entry inhibitors ...


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Akira Nakao, Kentoku Gotanda, Kazumasa Aoki, Shimpei Hirano, Yoshiharu Hiruma, Takeshi Shiiki: Indanyl compounds. Daiichi Sankyo Company, Christensen O Connor Johnson Kindness PLLC, May 22, 2012: US08183272

Compounds exhibiting calcium receptor antagonist activity that are safe and orally administrable having Formula (I) or pharmaceutically acceptable salts thereof:


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Sanchez Jean Yves, Langlois Bernard, Medebielle Maurice, Toulgoat Fabien, Paillard Elie, Alloin Fannie, Iojoiu Christina: Sulfonylimidures aromatiques et leur preparation.. Inst Nat Polytech Grenoble, Eras Labo, Univ Claude Bernard Lyon, January 18, 2008: FR2903692-A1

L'invention concerne des sulfonylimidures aromatiques, leur préparation, leur utilisation comme sel d'un électrolyte.Les sulfonylimidure répondent à la formule formule [R-SO2-N-SO2R'] rM (I). R est un groupe Ar-Zz-L- ; R' est un groupe perfluoroalkyle ou un groupe Ar'-Z'z'-L'- ; Z et Z' représentent ...


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Tamaki Kazuhiko, Yamaguchi Takahiro, Oda Kozo, Terasaka Tadao, Nakai Daisuke, Nakadai Masakazu: Benzene compound having two or more substituents. Sankyo, zoufeng lilian tao, December 26, 2007: CN200580045059

A superior LXR modulator is provided. A compound represented by the general formula (I): [wherein R 1 : -COR 9 (wherein R 9 : alkyl, optionally substituted alkoxy or optionally substituted amino); R 2 : H, OH, alkoxy, optionally substituted amino, etc.; R 3 : H, optionally substituted alkyl, cycloal ...


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玉木和彦, 山口孝弘, 小田晃造, 寺坂直生, 中井大介, 中台正和: 具有两个或更多取代基的苯化合物. 第一三共株式会社, 邹 锋, 李连涛, 中国专利代理, December 26, 2007: CN200580045059.1

本发明提供了一种优异的LXR调节剂。特别提供了由通式(I)代表的化合物[其中R1表示-COR9(其中R9表示烷基、任选取代的烷氧基或任选取代的氨基);R2表示H、OH、烷氧基、任选取代的氨基等;R3表示H、任选取代的烷基、环烷基、任选取代的烷氧基、任选取代的氨基、卤素等;R4和R5分别表示H、任选取代的烷基、卤素等;R6和R7分别表示H或烷基;R8表示-X2R10[其中R10表示-COR11(其中R11表示OH、任选取代的烷氧基、任选取代的氨基等)、-SO2R12(其中R12表示任选取代的烷基、任选取代的氨基等)、四唑-5-基等;X2表示单键、任选取代的亚烷基等];X1表示-NH-、-O-、- ...


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Lv Long, Tang Qinghong, Lv Qiang, Wang Xueyue, Fu Qunmei, Feng Xiao, Liu Jun: Oxo fluoroalkyl sulfamide compound and its preparing method and use. Shanghai Inst Of Organic Chemistry, Cas, wu shenzhong, November 8, 2006: CN200610027494

The present invention relates to oxo fluoroalkyl sulfonamide compound and its preparation process and use as household and farm chemical pesticide. Structurally, the compound is perfluoro sulfonamide compound with increased ether bond structure. It has simple synthesis process. The pesticidal activi ...


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吕 龙, 唐庆红, 吕 强, 王学跃, 付群梅, 冯 骁, 刘 军: 氧杂氟烷基磺酰胺类化合物、制备方法及其用途. 中国科学院上海有机化学研究所, 邬震中, 上海新天, November 8, 2006: CN200610027494.8

本发明是一种氧杂氟烷基磺酰胺类化合物、制备方法和作为卫生及农用化学杀虫剂的用途。其结构式如下:该化合物是在全氟磺酰胺化合物中增加醚键结构,合成方法简便,杀虫活性测试结果表明:既可增加化合物的杀蟑螂活性,又可增加化合物的防治稻飞虱的生物活性,可以用于制备卫生或农用化学杀虫剂。