1
Peter John Zanzucchi, Satyam Choudary Cherukuri, Sterling Edward McBride, Robert R Demers, Aaron W Levine, Barry Jay Thaler, Robert Leon Quinn, Paul Leonard Braun, William Chiang, Zhonghui Hugh Fan, Steven A Lipp, James R Matey: Liquid distribution system. Sarnoff Corporation, William J Burke, December 8, 1998: US05846396 (298 worldwide citation)

The present invention provides a liquid distribution system, which is useful in a number of contexts, including in accomplishing various synthetic, diagnostic and drug screening reactions. The distribution system can comprise an alpha reservoir and a beta reservoir, a first set of parallel and adjac ...


2
Robert Shartle, Donald Besemer, Michael Gorin: Capillary stop-flow junction having improved stability against accidental fluid flow. Biotrack, Cooley Godward Castro Huddleson & Tatum, July 27, 1993: US05230866 (264 worldwide citation)

A capillary stop-flow junction located in a housing at an end of a capillary passageway used to transport a liquid and at the beginning of a non-capillary internal chamber in the housing, in which the stop-flow junction contains an improvement which comprises 1) means for selectively trapping a gas ...


3
Norman F Sheppard Jr, Alec Mian, Gregory Kellogg, Stephen G Kieffer Higgins, Bruce L Carvalho: Affinity binding-based system for detecting particulates in a fluid. Gamera Bioscience, McDonnell Boehnen Hulbert & Berghoff, November 7, 2000: US06143247 (225 worldwide citation)

This invention provides methods an apparatus for detecting and quantifying particulate matter suspended in a fluid. Specifically, the invention provides an integrated, affinity-binding based, analytical system comprising a platform for performing an affinity-binding based assay for specifically bind ...


4
Julian Gubinski, John L Palmer: Sealing device and method for inhibition of flow in capillary measuring devices. Enzymatics, Finnegan Henderson Farabow Garrett & Dunner, January 11, 1994: US05278079 (223 worldwide citation)

A channel or chamber device having means for inhibiting flow of aqueous medium therein after the channel or chamber has been filled with aqueous medium. The device has a channel or chamber with a sample intake port at one end and an exhaust port at the other end. A restricted or reduced size chamber ...


5
Ken Tseung, Wai Bun Wong, Glenn K Takayama, Christopher M Jones, Krishan L Kalra: Automated staining apparatus. BioGenex Laboratories, Richard Neeley, Luann Cserr, August 8, 1995: US05439649 (219 worldwide citation)

An automated microscope-slide-staining apparatus, having a supporting framework; an arm moveable in three dimensions attached to the framework; apparatus for moving the arm; a hollow tip head located on the arm; apparatus for alternatively supplying positive or negative gas pressure to the hollow ti ...


6
Robert S Dubrow, Colin B Kennedy, Luc J Bousse: Microfluidic devices incorporating improved channel geometries. Caliper Technologies, Matthew B Murphy, Jonathan Alan The Law Offices of Jonathan Alan Quine Quine, May 30, 2000: US06068752 (213 worldwide citation)

The present invention generally provides microfluidic devices which incorporate improved channel and reservoir geometries, as well as methods of using these devices in the analysis, preparation, or other manipulation of fluid borne materials, to achieve higher throughputs of such materials through t ...


7
Wilson Robert: Disposable electrochemical sensor incorporating reagent. Wilson Robert, October 7, 1992: GB2254436-A (199 worldwide citation)

A disposable reactor (10) is provided for use with a co-operating instrument (20) to form an analytical device. The reactor includes a body of capillary material (14) housed in an enclosure (11, 15) having an opening for application of liquid to the body. At least one reagent (16) is immobilised in ...


8
Robert S Hillman, Ian Gibbons: Blood separation device comprising a filter and a capillary flow pathway exiting the filter. Biotrack, Leydig Voit & Mayer, June 28, 1988: US04753776 (197 worldwide citation)

A method for separating plasma from red blood cells and a device utilizing the method in which a low-pressure filter is interposed in a pathway between an inlet port and a reaction area. The sole driving force for the movement of plasma from the filter to the reaction area is capillary force provide ...


9
Robert S Matson, Peter J Coassin, Jang B Rampal, Edwin M Southern: Method and apparatus for creating biopolymer arrays on a solid support surface. Beckman Instruments, William H May, P R Harder, Janis C Henry, July 4, 1995: US05429807 (181 worldwide citation)

An automated method and apparatus for performing biopolymer synthesis on a two-dimensional support surface whereby a two-dimensional matrix or array of biopolymers are obtained on the surface. An applicator in the form of a thick plate having in a surface at least one cavity in the form of an open c ...


10
Peter Van Vlasselaer: Methods for enriching specific cell-types by density gradient centrifugation. Activated Cell Therapy, Carol A Stratford, Debra J Glaister, Peter J Dehlinger, November 24, 1998: US05840502 (154 worldwide citation)

The present invention relates to methods of enriching for desired cell population from cell sources, such as body fluids, dispersed tissue specimens and cultured cells. In particular, the present invention relates to the use of a cell-trap centrifugation tube containing a specific density gradient s ...