1
Mohamed SKIBA Mohamed SKIBA
Mohamed Skiba, Malika Lahiani, Frederic Bounoure, Pierre Dechelotte: Association of Oleaginous Substance With a Mixture of at Least Two Cyclodextrins. In Cyclo, Harness Dickey & Pierce, May 21, 2009: US20090130218-A1

The invention concerns a mixture of inclusion complexes comprising or consisting of (1) at least two different cyclodextrins selected among alpha-, beta- and gamma cyclodextrin and/or derivatives thereof, in particular derivatives thereof modified by primary and/or secondary hydroxyl groups, and (2) ...


2
Mohamed SKIBA Mohamed SKIBA
Skiba Mohamed, Skiba Malika, Bounoure Frédéric, Dechelotte Pierre: (Fr) Composition homogene et stable, riche en substances oleagineuses a base dun produit laitier, son procede de preparation et ses utilisations, (En) Homogeneous and stable composition rich in oleaginous substances based on a milk product, method for the preparation thereof and uses thereof. In Cyclo, Skiba Mohamed, Skiba Malika, Bounoure Frédéric, Dechelotte Pierre, BREDEMA, December 18, 2008: WO/2008/152226

(EN) The present invention relates to a stable and homogeneous milk composition based on milk comprising at least one cyclodextrin and at least one oleaginous substance. It also relates to the preparation thereof and also to products prepared therefrom, such as food compositions, powders, medicinal ...


3
Mohamed SKIBA Mohamed SKIBA
Skiba Mohamed, Skiba Malika, Bounoure Frederic, Dechelotte Pierre: Composition homogene et stable, riche en substances oleagineuses a base dun produit laitier, son procede de preparation et ses utilisations.. In Cyclo Soc Par Actions Simpl, November 14, 2008: FR2915901-A1

L'invention a pour objet une composition lactée stable et homogène à base de lait comprenant au moins une cyclodextrine et au moins une substance olagineuse. Elle concerne aussi sa préparation ainsi que des produits préparés à partir de celle-ci comme des compositions alimentaires, poudres, alicamen ...


4
James Doherty
Dorn Conrad P, Finke Paul E, Maccoss Malcolm, Doherty James B, Shah Shrenik K, Hagmann William K: New substituted azetidinones as anti-inflammatory and antidegenerative agents.. Merck & Co, April 22, 1992: EP0481671-A1 (40 worldwide citation)

New substituted azetidinones of the general formula (A') which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents are described. e


5
Stéphane De Lombaert
Stéphane De Lombaert, Michel Jose Emmanuel: Chymase Inhibitors. Boehringer Ingelheim International, Michael P Morris, Boehringer Ingelheim Usa Corporation, February 4, 2010: US20100029637-A1

Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.


6
Carini David John, Duncia John Jonas Vytautas: Angiotensin ii receptor blocking imidazoles.. Du Pont, January 20, 1988: EP0253310-A2 (316 worldwide citation)

Substituted imidazoles such as are useful as angiotensin II blockers. These compounds have activity in treating hypertension and congestive heart failure.


7
Bell Andrew Simon, Brown David, Terrett Nicholas Kenneth: Pyrazolopyrimidinone antianginal agents.. Pfizer, Pfizer, January 2, 1992: EP0463756-A1 (195 worldwide citation)

Compounds of the formula: wherein R is H, C1-C3 alkyl, C3-C5 cycloalkyl or C1-C3 perfluoroalkyl; R is H, C1-C6 alkyl optionally substituted by OH, C1-C3 alkoxy or C3-C6 cycloalkyl, or C1-C3 perfluoroalkyl; R is C1-C6 alkyl, C3-C6 alkenyl, C3-C6 alkynyl, C3-C7 cycloalkyl, C1-C6 perfluoroalkyl or (C3- ...


8
Chakravarty Prasun K, Greenlee William J, Mantlo Nathan B, Patchett Arthur A, Walsh Thomas F: Substituted imidazo-fused 6-membered heterocycles as angiotensin ii antagonists.. Merck & Co, December 5, 1990: EP0400974-A2 (191 worldwide citation)

Substituted Imidazo-fused 6-membered heterocycles of structural formula: wherein A, B, C, and D are independently carbon atoms or nitrogen atoms are angiotensin II antagonists useful in the treatment of hypertension and congestive heart failure.


9
Patchett Arthur A, Harris Elbert E, Wyvratt Matthew J, Tristram Edward W: Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them.. Merck & Co, June 25, 1980: EP0012401-A1 (181 worldwide citation)

Carboxyalkyl dipeptide derivatives and related compounds which are useful as antihypertensives, and having the formulae: wherein R and R are the same or different and are hydroxy, alkoxy, alkenoxy, dialkylamino alkoxy, acylamino alkoxy, acyloxy alkoxy, aryloxy, alkyloxy, substituted aryloxy or subst ...


10
Stjernschantz Johan W, Resul Bahram: Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension.. Pharmacia, April 18, 1990: EP0364417-A1 (173 worldwide citation)

The invention relates to ophthalmological compositions for topical treatment of glaucoma or ocular hypertension comprising an effective intraocular pressure reducing amount of a prostaglandin derivative of PGA, PGB, PGD, PGE or PGF, in which the omega chain contains a ring structure, in an ophthalmo ...