1
Reese S Terry Jr, Joachim F Wernicke: Therapeutic treatment of sleep disorder by nerve stimulation. Cyberonics, O Connor Cavanagh et al, August 9, 1994: US05335657 (872 worldwide citation)

Method and apparatus for treating and controlling sleep disorders by detecting the presence of the sleep disorder under treatment, and, in response, selectively applying a predetermined electrical signal to the patient's vagus nerve for stimulation thereof to alleviate the sleep disorder under treat ...


2
Joseph H Schulman, Gerald E Loeb, John C Gord, Primoz Strojnik: Structure and method of manufacture of an implantable microstimulator. Alfred E Mann Foundation for Scientific Research, L Lee Humphries, March 16, 1993: US05193540 (690 worldwide citation)

An implantable microstimulator has a structure which is manufactured to be substantially encapsulated within a hermetically-sealed housing inert to body fluids, and of a size and shape capable of implantation in a living body, by expulsion through a hypodermic needle. The internal structure of the m ...


3
Joachim F Wernicke, Reese S Terry Jr: Treatment of endocrine disorders by nerve stimulation. Cyberonics, August 3, 1993: US05231988 (659 worldwide citation)

Method and apparatus are described for treating and controlling diabetes and other systemic pancreatic endocrine disorders attributable to abnormal levels of secretion of endogenous insulin. An electrical stimulator implanted into or worn external to the patient's body is adapted, when activated, to ...


4
Robert E Fischell, David R Fischell, Adrian R M Upton: System for treatment of neurological disorders. NeuroPace, January 18, 2000: US06016449 (630 worldwide citation)

Disclosed is a multiple electrode, closed-loop, responsive system for the treatment of certain neurological diseases such as epilepsy, migraine headaches and Parkinson's disease. Brain electrodes would be placed in close proximity to the brain or deep within brain tissue. When a neurological event s ...


5
Joseph H Schulman, Primoz Strojnik, Paul Meadows: Implantable microdevice with self-attaching electrodes. Alfred E Mann Foundation for Scientific Research, Fitch Even Tabin & Flannery, October 25, 1994: US05358514 (611 worldwide citation)

An implantable microminiature stimulator and/or sensor (microdevice) is housed within a sealed housing that includes all the requisite electronic circuitry for inductively receiving power and control signals to sense of biopotential or other biomedical signals and/or to generate electrical stimulati ...


6
Ivan Osorio, Mark G Frei: Vagal nerve stimulation techniques for treatment of epileptic seizures. Banner & Witcoff, January 22, 2002: US06341236 (588 worldwide citation)

A system and method for using electrical stimulation of the vagus nerve to treat epilepsy with minimized or no effect on the heart. Treatment is carried out by an implantable signal generator, one or more implantable electrodes for electrically stimulating a predetermined stimulation site of the vag ...


7
Jacob Zabara: Heart rhythm stabilization using a neurocybernetic prosthesis. Panitch Schwarze Jacobs & Nadel P C, December 23, 1997: US05700282 (585 worldwide citation)

Heart rhythm is stabilized within the heart's free running cycle by detecting arrhythmias in a mammalian subject, and then electronically stimulating the subject's vagus and cardiac sympathetic nerves. More specifically, vagus efferents are stimulated to directly cause heart rate to slow down, while ...


8
Reese S Terry Jr, Joachim F Wernicke, Ross G Baker Jr: Therapeutic treatment of migraine symptoms by stimulation. Cyberonics, Leitner Greene & Christensen, June 1, 1993: US05215086 (578 worldwide citation)

Method and apparatus for treating and controlling migraine by selectively applying a predetermined electrical signal to the patient's vagus nerve for stimulation thereof to alleviate the migraine attack. The signal is a pulse waveform having parameters programmed to desynchronize the patient's EEG i ...


9
Michael Sasha John: Adaptive brain stimulation method and system. Cooper & Dunham, October 8, 2002: US06463328 (562 worldwide citation)

Adaptive brain stimulation systems and methods aids in the rehabilitation of patients from traumatic brain injury, coma, movement disorder, or other brain dysfunction. After a direct brain stimulator is implanted in a brain region of a patient, the patient is stimulated according to a set of stimula ...


10
Joseph H Schulman, Gerald E Loeb, John C Gord, Primoz Strojnik: Implantable microstimulator. Alfred E Mann Foundation For Scientific Research, Fitch Even Tabin & Flannery, June 28, 1994: US05324316 (558 worldwide citation)

An addressable, implantable microstimulator is substantially encapsulated within a hermetically-sealed housing inert to body fluids, and of a size and shape capable of implantation in a living body, by expulsion through a hypodermic needle. Power and information for operating the microstimulator is ...