11
Joel E Sivula, Robert A Betzold: Method and apparatus for implementing activity sensing in a pulse generator. Medtronic, October 1, 1991: US05052388 (267 worldwide citation)

A cardiac pacemaker system of the type including a sensor responsive to the metabolic demand for oxygen and which varies the pacing rate in response to the output of the sensor. The pacemaker defines a function relating sensor output to pacing rate, based upon independently selectable parameters, in ...


12
Jiang Ding, Yinghong Yu, Andrew P Kramer, Julio Spinelli: Cardiac pacing using adjustable atrio-ventricular delays. Cardiac Pacemakers, Schwegman Lundberg Woessner & Kluth P A, April 1, 2003: US06542775 (265 worldwide citation)

A pacing system for providing optimal hemodynamic cardiac function for parameters such as contractility (peak left ventricle pressure change during systole or LV+dp/dt), or stroke volume (aortic pulse pressure) using system for calculating atrio-ventricular delays for optimal timing of a ventri ...


13
Euljoon Park, Gene A Bornzin, Joseph J Florio, Kerry Bradley, William Gibb: Implantable cardiac stimulation device and method for varying pacing parameters to mimic circadian cycles. Pacesetter, October 3, 2000: US06128534 (246 worldwide citation)

Provided herein are methods and apparatus for automatically adjusting pacing parameters in implantable programmable stimulation devices, such as rate-responsive pacemakers and cardioverter defibrillators. The methods and apparatus provide a circadian varying pacing parameter (e.g., pacing rate, AV D ...


14
Rodney W Salo, Bruce A Tockman, Morton M Mower: Implantable cardiac function monitor and stimulator for diagnosis and therapy delivery. Cardiac Pacemakers, Haugen and Nikolai, May 23, 1995: US05417717 (246 worldwide citation)

An implantable monitor/stimulator is disclosed that monitors and assesses indices of cardiac function, including the strength and timing of cardiac contraction, then automatically executes a physician-selected mode of therapy. It accomplishes this by assessing impedance, electrocardiogram, and/or pr ...


15
Stephen Denker, Arthur J Beutler: Intravenous cardiac pacing system with wireless power supply. Kenergy, George E Haas, Quarles & Brady, February 21, 2006: US07003350 (242 worldwide citation)

A cardiac pacemaker includes a power transmitter which periodically transmits a pulse of a radio frequency signal to a vascular electrode-stent that is implanted in a vein or artery of an animal. The vascular electrode-stent employs energy from the radio frequency signal to charge a storage device w ...


16
Jean Luc Bonnet: Active implantable medical device for treating sleep apnea syndrome by electrostimulation. Ela Medical, Orrick Herrington & Sutcliffe, June 3, 2003: US06574507 (241 worldwide citation)

An active implantable medical device for electrostimulation in response to a determined sleep apnea syndrome, particularly a pacemaker. This device measures the respiratory activity of the patient, using for example, a minute ventilation sensor and/or a blood oxygen saturation sensor, and analyzes t ...


17
Ivan Osorio, Mark G Frei: Vagal nerve stimulation techniques for treatment of epileptic seizures. Banner & Witcoff, July 1, 2003: US06587727 (237 worldwide citation)

The present invention uses electrical stimulation of the vagus nerve to treat epilepsy with minimized or no effect on the heart. Treatment is carried out by an implantable signal generator, one or more implantable electrodes for electrically stimulating a predetermined stimulation site of the vagus ...


18
Todd J Cohen: System for and method of treating a malfunctioning heart. Leonard Bloom, Leonard Bloom, July 19, 1994: US05330505 (218 worldwide citation)

A system for treating the malfunctioning heart of a patient includes means which derive at least one electrical signal from the patient's heart and means which derive at least two physiologic signals from or related to the patient's circulatory system. The physiologic signals, or functions thereof, ...


19
John A Hauck, Arthur L Olive: Rate adaptive cardiac rhythm management device control algorithm using trans-thoracic ventilation. Cardiac Pacemakers, Haugen and Nikolai, June 7, 1994: US05318597 (218 worldwide citation)

A rate adaptive cardiac rhythm management device in which the pacing rate is adjusted in accordance with changes in the patient's minute ventilation. An adaptive four-pole elliptic digital filter, preferably implemented in software, functions to attenuate any signal components due to cardiac activit ...


20
Rodney W Salo: Method and apparatus for pacing patients with severe congestive heart failure. Cardiac Pacemakers, Haugen and Nikolai P A, December 23, 1997: US05700283 (216 worldwide citation)

An implantable cardiac pacemaker especially designed for treatment of CHF includes an accelerometer for sensing heart sounds and processing circuitry for deriving from the heart sound information the mechanical AV delay of the patient's heart. The pacemaker's applied AV delay is then adjusted until ...