1
Robert S Kieval, Tom D Bettett, Stephanie Michele Fitts: Baroreflex modulation with carotid sinus nerve stimulation for the treatment of heart failure. Medtronic, Harold R Patton, Reed A Duthler, June 6, 2000: US06073048 (473 worldwide citation)

A system and method for stimulating the baroreflex arc based on levels of indicators from the body includes a pacemaker for bradycardia support pacing should the indicators show the need for support pacing. Other indicators and a process take advantage of an assumed relationship between peripheral v ...


2
Todd J Sheldon: Medical service employing multiple DC accelerometers for patient activity and posture sensing and method. Medtronic, Reed A Duthler, Harold R Patton, January 14, 1997: US05593431 (374 worldwide citation)

A method of and apparatus for determining the physical posture of a patient's body, having a superior-inferior body axis, an anterior-posterior body axis and a lateral-medial body axis, in relation to earth's gravitational field. A medical device having first, second and, optionally, third DC accele ...


3
Robert S Kieval: System for providing hyperpolarization of cardiac to enhance cardiac function. Medtronic, Harold R Patton, Michael B Atlass, September 1, 1998: US05800464 (342 worldwide citation)

An implantable system providing cardiac anodal stimulation (AS) as a system for effecting hyperpolarization of myocardial cells of a heart chamber to enhance the relaxation thereof in the diastolic phase and to thereby enhance cardiac function. The AS system is optimally timed to be delivered in an ...


4
Gerrard M Carlson, Veerichetty A Kadhiresan, Julio C Spinelli: Heart rate variability as an indicator of exercise capacity. Cardiac Pacemakers, Nikolai Merserau & Dietz P A, February 15, 2000: US06026320 (337 worldwide citation)

Based upon patient studies indices a high degree of correlation was found between HRV and VO2.sub.max, i.e., the patient's exercise capacity. Based on this finding, a pacing therapy optimization protocol for treating patients with CHF has been devised. The protocol involves first pacing the patient' ...


5
Bruce A Tockman, Julio C Spinelli, Rodney W Salo: Method and apparatus to automatically optimize the pacing mode and pacing cycle parameters of a dual chamber pacemaker. Cardiac Pacemakers, Haugen and Nikolai P A, July 30, 1996: US05540727 (324 worldwide citation)

A cardiac stimulating system incorporating a microprocessor-based controller is designed to automatically optimize both the pacing mode and one or more pacing cycle parameters in a way that results in optimization of a cardiac performance parameter, such as cardiac output. For each of a plurality of ...


6
Lawrence S Baumann, Bruce A Tockman, Rodney W Salo, Emanuel H Silvermint: Apparatus and method for optimizing cardiac performance by determining the optimal timing interval from an accelerometer signal. Cardiac Pacemakers, Haugen & Nikolai PA, November 17, 1998: US05836987 (323 worldwide citation)

A cardiac stimulating apparatus and method which optimizes cardiac performance by determining, from a filtered waveform transmitted from an accelerometer contained within the cardiac pacer, an optimum timing interval between at least one of intrinsic and paced stimulations of pre-selected chambers o ...


7
Gene A Bornzin, Elia R Arambula, Joseph J Florio: System and method for modulating the base rate during sleep for a rate-responsive cardiac pacemaker. Pacesetter, Lisa P Weinberg, December 19, 1995: US05476483 (323 worldwide citation)

A system and method are provided for modulating the base rate of a transfer function for a rate-responsive cardiac pacemaker. Activity sensor measurements are used to derive activity variance measurements, which in turn are used to modulate the base pacing rate. In one embodiment, a histogram is use ...


8
Tom D Bennett, Russell L Lundstrom Jr, Paul M Stein: Post-extrasystolic potentiation stimulation with physiologic sensor feedback. Medtronic, Dwight N Holmbo, Harold R Patton, May 25, 1993: US05213098 (320 worldwide citation)

A post-extrasystolic potentiation (PESP) cardiac pacing energy stimulator for applying paired and/or triggered pacing stimulation pulses to the right atrium and/or ventricle incorporating one or more sensors, such as a venous oxygen saturation, ventricular, atrial, or arterial blood pressure, or int ...


9
Andrew P Kramer, Jeffrey E Stahmann, Rene H Wentkowski, Kenneth L Baker, Jesse W Hartley, David B Krig: System providing ventricular pacing and biventricular coordination. Cardiac Pacemakers, Schwegman Lundberg Woessner & Kluth P A, September 4, 2001: US06285907 (294 worldwide citation)

A cardiac rhythm management system includes techniques for computing an indicated pacing interval, AV delay, or other timing interval. In one embodiment, a variable indicated pacing interval is computed based at least in part on an underlying intrinsic heart rate. The indicated pacing interval is us ...


10
Tadashi Fujii, Shinji Ishida: Cardiac pacemaker using wireless transmission. Terumo Kabushiki Kaisha, Burns Doane Swecker & Mathis, May 2, 1995: US05411535 (279 worldwide citation)

A cardiac pacemaker improved to reduce the weight and size and to unburden the wearer of the pacemaker, while ensuring safe transmission of signals. The cardiac pacemaker includes a cardiac pacemaker main body 100 having at least two electrodes for detecting cardio-information, a control section for ...