1
Berg Eric P, Tuch Ronald J, Dror Michael, Wolff Rodney G: Intravascular stents.. Medtronic, November 9, 1994: EP0623354-A1 (475 worldwide citation)

The invention provides a method for making an intravascular stent by applying to the body of a stent a solution which comprises a solvent, a polymer dissolved in the solvent and a therapeutic substance dispersed in the solvent and then evaporating the solvent. The inclusion of a polymer in intimate ...


2
Hossainy Syed F A, Roller Mark B, Llanos Gerard H, Kopia Gregory A: Process for coating stents. Ethicon, January 12, 2000: EP0970711-A2 (430 worldwide citation)

A process is provided for coating stents having a first and second surface with passages there between to avoid blockage and bridging of the passages. The process comprises contacting the stent with a liquid coating solution containing a film forming biocompatible polymer under conditions suitable t ...


3
Ding Ni: Method and apparatus for applying drug-release coatings. Schneider Usa, July 1, 1998: EP0850651-A2 (284 worldwide citation)

The invention is directed to a method of applying drug-release coatings whereby a polymer can be dissolved in a first solvent (solvent A) to form a polymer system and a drug can be dissolved or suspended in a second solvent (solvent B) to form a drug system. The coating or layer of coating so formed ...


4
Ding Ni, Helmus Michael N: Drug coating with topcoat. Schneider Usa, June 23, 1999: EP0923953-A2 (245 worldwide citation)

A coating and method for a coating an implantable device or prostheses are disclosed. The coating includes an undercoat of polymeric material containing an amount of biologically active material, particularly heparin, dispersed therein. The coating further includes a topcoat which covers less than t ...


5
Ishii Naoki, Togawa Hideyuki: Stent. Terumo, January 8, 2003: EP1273314-A1 (243 worldwide citation)

A stent wherein a biologically/physiologically active substance is loaded on the stent main body in a stable manner is provided. The biologically/physiologically active substance does not undergo decomposition or degradation, the biologically/physiologically active substance is gradually released fo ...


6
Ding Ni, Trinh Tuyethoa Thi, Raeder Devens Jennifer E: Drug-releasing coatings for medical devices. Schneider Usa, November 25, 1998: EP0879595-A2 (242 worldwide citation)

The invention is directed to medical devices having a drug-releasing coating and methods for making such coated devices. The coating permits timed or prolonged pharmacological activity on the surface of medical devices through a reservoir concept. Specifically, the coating comprises at least two lay ...


7
Wright Carol, Llanos Gerard H, Rakos Ronald, King Kirsten: Stent with local rapamycin delivery. Cordis, October 20, 1999: EP0950386-A2 (232 worldwide citation)

Delivery of rapamycin locally, particularly from an intravascular stent, directly from micropores in the stent body or mixed or bound to a polymer coating applied on stent, to inhibit neointimal tissue proliferation and thereby prevent restenosis. This invention also facilitates the performance of t ...


8
Ding Ni, Helmus Michael N: Drug release stent coating and process. Schneider Usa, April 1, 1998: EP0832655-A2 (231 worldwide citation)

A coating and method for implantable open lattice metallic stent prostheses are disclosed. The coating includes a relatively thin layer of biostable elastomeric material containing an amount of biologically active material particularly heparin, dispersed in the coating in combination with a non-thro ...


9
Llanos Gerard H, Roller Mark B, Scopelianos Angelo: Coating for medical devices. Ethicon, April 3, 2002: EP1192957-A2 (223 worldwide citation)

The present invention includes biocompatible coatings and films for use on implantable medical devices and medical devices containing such coatings and films applied to a surface thereof, which coatings/films are present on the device in an amount effective to provide an inert surface to be in conta ...


10
Dinh Thomas Q, Tuch Ronald J, Schwartz Robert S: Drug eluting stent. Medtronic, March 20, 1996: EP0701802-A1 (219 worldwide citation)

A drug eluting intravascular stent comprising: (a) a generally cylindrical stent body; (b) a solid composite of a polymer and a therapeutic substance in an adherent layer on the stent body; and (c) fibrin in an adherent layer on the composite. This may be prepared by the steps of: (a) providing a ge ...