Benjamin Oshlack, Frank Pedi Jr, Mark Chasin: Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer. Euroceltigue, Steinberg & Raskin, December 28, 1993: US05273760 (279 worldwide citation)

A stabilized solid controlled release dosage form having a coating derived from an aqueous dispersion of ethylcellulose is obtained by overcoating a substrate including a therapeutically active agent with an aqueous dispersion of ethylcellulose and then curing the coated substrate at a temperature a ...

Benjamin Oshlack, Mark Chasin, Frank Pedi Jr: Controlled-release formulations coated with aqueous dispersions of ethylcellulose. Euroceltique, Steinberg Raskin & Davidson, December 5, 1995: US05472712 (270 worldwide citation)

A stabilized solid controlled release formulation having a coating derived from an aqueous dispersion of a hydrophobic polymer is obtained by overcoating a substrate including an active agent selected from the group consisting of a systemically active therapeutic agent, a locally active therapeutic ...

Benjamin Oshlack, Mark Chasin: Immediate release tablet cores of insoluble drugs having sustained-release coating. Euro Celtique, Steinberg Raskin & Davidson, March 19, 1996: US05500227 (197 worldwide citation)

A controlled release tablet for oral administration is disclosed which has a tablet core including an insoluble therapeutically active agent having an aqueous solubility of less than or equal to about 5 mg/ml in a sufficient amount to render a therapeutic effect. The core provides rapid release of s ...

Robert S Goldie, Sandra T A Malkowska, Stewart T Leslie, Ronald B Miller: Controlled release hydromorphone composition. Euroceltique, Steinberg & Raskin, July 4, 1989: US04844909 (179 worldwide citation)

A solid controlled release, oral dosage form, the dosage form comprising a therapeutically effective amount of hydromorphone or a salt thereof in a matrix wherein the dissolution rate in vitro of the dosage form, when measured by the USP Paddle Method at 100 rpm in 900 ml aqueous buffer (pH between ...

Tadashi Makino, Tetsuro Tabata, Shin ichiro Hirai: Spherical granules having core and their production. Takeda Chemical, Wegner Cantor Mueller & Player, June 25, 1991: US05026560 (162 worldwide citation)

The spherical granules having a core coated with spraying powder containing a drug and low substituted hydroxypropylcellulose, because of their excellent hardness, can be coated further evenly, (e.g. sustained release coating, gastric coating, enteric coating), and at the time the granules are excel ...

Gerald Benedikt: New oral form of medicament and a method for producing it. Byk Gulden Lomberg Chemische Fabrik, Berman Aisenberg & Platt, April 11, 1978: US04083949 (125 worldwide citation)

An oral form of medicament releases active substance in the gastrointestinal tract at a constant rate.

Anthony W Jenkins, Stewart T Leslie, Ronald B Miller: Oral pharmaceutical composition through mucosa. Euroceltique, Steinberg & Raskin, July 10, 1990: US04940587 (122 worldwide citation)

An arrangement is provided for the application of an oral pharmaceutical to the mucosa of the oral or nasal cavity, for sustained release there of the drug. The arrangement of the invention comprises a body which has a size and shape suitable for insertion into and retention in the oral or nasal cav ...

Ubaldo Conte, Aldo La Manna, Paolo Colombo: Tablets with controlled-rate release of active substances. Jagotec, Birch Stewart Kolasch & Birch, June 6, 1995: US05422123 (105 worldwide citation)

Tablets with zero order controlled-rate of release of the active substances, consisting of a core of defined geometrical form containing the active substance, polymer substances which swell on contact with aqueous liquids and polymer substances with gelling properties, and a support applied to said ...

Ubaldo Conte, Aldo La Manna, Lauretta Maggi: Pharmaceutical tablet capable of liberating one or more drugs at different release rates. Jagotec, Kenyon & Kenyon, April 14, 1998: US05738874 (90 worldwide citation)

Pharmaceutical tablet consisting of a first layer containing one or more drugs with immediate or controlled release formulation, a second layer containing one or more drugs, either equal to or different from the first layer, with slow release formulation, and a low-permeability barrier-type layer co ...

Paul C Guley, Richard J DeNeale, George Milosovich: Sustained release pharmaceutical compositions. American Home Products Corporation, Adley F Mandel, January 5, 1982: US04309405 (90 worldwide citation)

Novel sustained release compositions comprising a core containing a drug, a seal coating surrounding the core and a sugar coating surround the seal coated core are disclosed.