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Stéphane De Lombaert
DE LOMBAERT Stéphane, LIU Weimin, LO Ho Yin, NEMOTO Peter Allen: INHIBITEURS BENZIMIDAZOLE DE PRODUCTION DE LEUCOTRIÈNES, BENZIMIDAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION. BOEHRINGER INGELHEIM INTERNATIONAL, DE LOMBAERT Stéphane, LIU Weimin, LO Ho Yin, NEMOTO Peter Allen, MORRIS Michael P, May 10, 2012: WO/2012/061169 (1 worldwide citation)

The present invention relates to compounds of formula (IA), (IB) and (IC) and pharmaceutically acceptable salts thereof, wherein R1-R7 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of var ...


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Chakravarty Prasun K, Patchett Arthur A, Camara Valerie J, Walsh Thomas F, Greenlee William J: Substituted benzimidazoles as angiotensin ii antagonists.. Merck & Co, December 5, 1990: EP0400835-A1 (113 worldwide citation)

There are disclosed new substituted benzimidazole compounds and derivatives thereof which are useful as angiotensin II antagonists. These compounds have the general formula: l


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Narr Berthold Dr Dipl Chem, Bomhard Andreas Dr Dipl Chem, Hauel Norbert Dr Dipl Chem, Van Meel Jacques Dr, Wienen Wolfgang Dr Dipl Biol, Entzeroth Michael Dr Dipl Chem: Benzimidazoles, drugs containing these compounds and process for their preparation.. Thomae Dr K, October 17, 1990: EP0392317-A2 (78 worldwide citation)

The invention relates to benzimidazoles of the formula in which R1 to R6 are defined as in claim 1, their 1- and 3-isomer mixtures and their acid addition salts, which have useful properties. The novel compounds are in particular angiotensin II antagonists.


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ZENG QINGBEI: Antiviral compounds composed of three linked aryl moieties to treat diseases such as hepatitis c. SCHERING CORPORATION, Bergman Jeffrey P, December 2, 2010: WO/2010/138791 (75 worldwide citation)

The present invention relates to novel Linked Tricyclic Aryl Compounds, compositions comprising at least one Linked Tricyclic Compound, and methods of using Linked Tricyclic Aryl Compounds for treating or preventing HCV infection in a patient. in one aspect, the present invention provides Compounds ...


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Roberts David Anthony, Russell Simon Thomas: Benzimidazole derivatives.. Ici, November 28, 1990: EP0399732-A1 (74 worldwide citation)

The invention concerns heterocyclic compounds of the formula I (and their physiologically acceptable salts), together with pharmaceutical compositions containing them. The heterocyclic compounds antagonise the actions of angiotensin II and are of value in treating diseases or medical conditions such ...


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CHEN KEVIN X: Antiviral compounds composed of three aligned aryl moieties to treat diseases such as hepatitis c. SCHERING CORPORATION, Meade Eric A, December 2, 2010: WO/2010/138790 (72 worldwide citation)

The present invention relates to novel Tricyclic Compounds, compositions comprising at least one Tricyclic Compound, and methods of using Tricyclic Compounds for treating or preventing a viral infection or a virus-related disorder in a patient. The present invention provides Tricyclic Compounds of F ...


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Lovgren Kurt Ingmar, Pilbrant Ake Gunnar, Yasumura Mitsuru, Morigaki Satoshi, Oda Minoru, Ohishi Naohiro: New pharmaceutical preparation for oral use.. Haessle, December 2, 1987: EP0247983-A2 (72 worldwide citation)

Pharmaceutical preparation containing omeprazole together with an alkaline compound or an alkaline salt of omeprazole optionally together with an alkaline compound as the core material, one or more subcoating layers comprising inert reacting compounds which are soluble or rapidly disintegrating in w ...


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Bressi Jerome C, Brown Jason W, Cao Sheldon X, Gangloff Anthony R, Jennings Andrew J, Stafford Jeffrey A, Vu Phong H, Xiao Xiao Yi: Histone deacetylase inhibitors. Syrrx, Bressi Jerome C, Brown Jason W, Cao Sheldon X, Gangloff Anthony R, Jennings Andrew J, Stafford Jeffrey A, Vu Phong H, Xiao Xiao Yi, WEITZ David J, September 30, 2004: WO/2004/082638 (67 worldwide citation)

Compounds that may be used to inhibit histone deacetylase having the formula (I) or formula (II) wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remaind ...


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Miyake Kazutoshi, Matsukura Masayuki, Yoneda Naoki, Hiroshima Osamu, Mori Nobuyuki, Ishihara Hiroki, Musha Takashi, Matsuoka Toshiyuki, Hamano Sachiyuki, Minami Norio: Biphenylmethane derivative, the use of it and pharmacological compositions containing same.. Eisai, April 3, 1991: EP0420237-A1 (67 worldwide citation)

The biphenylmethane derivative having the formula (I) is disclosed in which R1 is hydrogen, an alkyl, a cycloalkyl, a halogenated alkyl, -S-R7, -SO2-R7, -C IDENTICAL C-R7 or -(CH2)p-OR7, R7 being hydrogen, an alkyl, a cycloalkyl or a halogenated alkyl, p being zero or 1, -A1=A2-A3=A4- is -CH=CH-CH=C ...