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James Doherty
Dorn Conrad P, Finke Paul E, Maccoss Malcolm, Doherty James B, Shah Shrenik K, Hagmann William K: New substituted azetidinones as anti-inflammatory and antidegenerative agents.. Merck & Co, April 22, 1992: EP0481671-A1 (40 worldwide citation)

New substituted azetidinones of the general formula (A') which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents are described. e


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Stéphane De Lombaert
Rajagopal Bakthavatchalam, Timothy M Caldwell, Bertrand L Chenard, Stéphane De Lombaert, Kevin J Hodgetts: Substituted quinolin-4-ylamine analogues. Neurogen Corporation, Edward Angell Palmer & Dodge, November 19, 2009: US20090286767-A1

Substituted quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion ...


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Holton Robert A: Method for preparation of taxol.. Univ Florida State, December 5, 1990: EP0400971-A2 (136 worldwide citation)

A beta -lactam of the formula: wherein R1 is aryl, substituted aryl, alkyl, alkenyl, or alkynyl; R2 is hydrogen, alkyl, acyl, acetal, ethoxyethyl, or other hydroxyl protecting group; and R3 is aryl, substituted aryl, alkyl, alkenyl, or alkynyl; and process for the preparation of taxol comprising con ...


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Egbertson Melissa S, Hartman George D, Halczenko Wasyl, Laswell William L: Novel fibrinogen receptor antagonists.. Merck & Co, April 1, 1992: EP0478328-A1 (101 worldwide citation)

A series of non-peptide derivatives that are antagonists of the fibrinogen IIb/IIIa receptor and thus are platelet aggregation compounds useful in the prevention and treatment of diseases caused by thrombus formation.


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Culbertson Townley P, Mich Thomas F, Domagala John M, Nichols Jeffrey B: Antibacterial agents.. Warner Lambert Co, April 25, 1984: EP0106489-A2 (73 worldwide citation)

Novel naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediates used in the manufacture of the antibacteri ...


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Shuman Robert Theodore: Antithrombotic agents.. Lilly Co Eli, May 19, 1993: EP0542525-A2 (68 worldwide citation)

Thrombin inhibitors represented by the formula as provided wherein A is e.g. phenylglycyl, and phenylalanyl, a-methylphenylalanine and a-methylphenylglycine wherein the amino group is preferably substituted with lower alkyl alkanoyl or lower alkoxycarbonyl, or a bicyclo group e.g. 1,2,3,4-tetrahydro ...


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