Feijen Jan, Esselbrugge Hilbert: Article for the controlled delivery of an active substance, comprising a hollow space fully enclosed by a wall and filled in full or in part with one or more active substances.. Akzo, November 25, 1992: EP0514406-A1 (190 worldwide citation)

An article for the controlled delivery of an active substance, comprising a hollow space fully enclosed by a wall and filled in full or in part with one or more active substances, which wall is made using a biodegradable polymeric material permeable to the active substance, wherein the wall is compo ...

Moreau Jacques Pierre, Kitchell Judith P: Delivery system.. Biomeasure, February 1, 1989: EP0301856-A2 (180 worldwide citation)

A delivery system for agents, such as therapeutic agents, or other substances includes a biodegradable polymer and the agent or substance. The delivery system is coated with a barrier substance that decreases the quantity of the agent release from the system, compared to the quantity of the agent re ...

Kent John Scott, Sanders Lynda Mary, Lewis Danny Harvey, Tice Thomas Robert: Microencapsulation of water soluble polypeptides.. Syntex, May 26, 1982: EP0052510-A2 (168 worldwide citation)

This invention concerns novel sustained release microcapsule compositions comprising water-soluble, hormonally active polypeptides and optionally, a polymer hydrolysis modifying agent encapsulated in biocompatable, biodegradable polymers such as poly(lactide-co-glycolide) copoly

Oshlack Benjamin, Chasin Mark: Orally administrable opioid formulations having extended duration of effect.. Euro Celtique, April 12, 1995: EP0647448-A1 (161 worldwide citation)

Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesic contains a plurality of substrates includin ...

Deluca Patrick P: Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer.. Univ Kentucky Res Found, January 22, 1992: EP0467389-A2 (119 worldwide citation)

A drug delivery system for controlled release of a protein or polypeptide comprising a hydrophobic biodegradable polymer and a protein or polypeptide. A physical interaction is present between the polymer and the protein or polypeptide, thus, allowing protection and controlled release of the protein ...

Morella Angel Mario, Fisher Mark Christopher: Sustained release pharmaceutical composition.. Faulding F H &, July 11, 1990: EP0377518-A2 (118 worldwide citation)

A sustained release pharmaceutical pellet composition suitable for treating pain-associated conditions in patients comprises a core element including at least one active ingredient of high solubility; and a core coating for the core element which is partially soluble at a highly acidic pH to provide ...

Jenkins Anthony William, Leslie Stewart Thomas, Miller Ronald Brown: Oral pharmaceutical composition.. Euro Celtique, December 17, 1986: EP0205282-A2 (116 worldwide citation)

A sustained release, oral pharmaceutical composition in solid unit dosage form, for application to the mucosa of the oral or nasal cavity, comprises compressed, mucosa adhesive cellulose, coated granules, the granules comprising a drug, a higher aliphatic alcohol and a hydrated water soluble hydroxy ...

Oshlack Benjamin: Controlled release bases for pharmaceuticals.. Euro Celtique, January 20, 1988: EP0253104-A1 (105 worldwide citation)

The release of therapeutically active agents from controlled release bases is extended by using a combination of a higher aliphatic alcohol and an acrylic resin as the base material.


Bondi Joseph V: Drug delivery device.. Merck & Co, July 10, 1985: EP0147780-A2 (100 worldwide citation)

Polyvinyl alcohol for use as a film coating, a matrix for monolithic device or as a barrier coating for the preparation of controlled release drug delivery systems.