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Lone Jeppesen, Paul Stanley Bury, John Patrick Mogensen, Ingrid Pettersson, Per Sauerberg: Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives. Novo Nordisk, Rosemarie R Wilk Orescan, Reza Green, Richard W Book, March 22, 2005: US06869967 (7 worldwide citation)

Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of c ...


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Ching jer Chang, Curtis L Ashendel, Darrick Kim: Selenophene anti-tumor agents. Purdue Research Foundation, Barnes & Thornburg, May 17, 2005: US06894039 (4 worldwide citation)

Novel selenophene compounds useful as anti-tumor agents are described. Preferred compounds include compounds of formula I: wherein R1 and R2 are independently selected from the group consisting of;  H, CHO, CH2OH and CH2NH2; and X and Y are independently selected from the group consisting of Se, S, ...


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Niels Peter Hundahl Møller, Henrik Sune Andersen, Lars Fogh Iversen, Ole Hvilsted Olsen, Sven Branner, Daniel Dale Holsworth, Farid Bakir, Luke Milburn Judge, Frank Urban Axe, Todd Kevin Jones, William Charles Ripka, Yu Ge, Roy Teruyuki Uyeda: Benzo[b]thiophenyl or tetrahydro-benzo[b]thiophenyl modulators of protein tyrosine phosphatases (PTPases). Novo Nordisk, Rosemarie R Wilk Orescan, Reza Green, Richard W Bork, October 4, 2005: US06951878 (3 worldwide citation)

The present invention provides novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. The ...


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Stephen L Schlesinger: Use of leukotriene receptor antagonist for treatment of scarring. October 4, 2005: US06951869 (2 worldwide citation)

A method of preventing or treating either scarring or capsular contractures in subjects in need of such treatment comprising the administration of leukotriene receptor antagonists to said subject in need of treatment.


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Pascal Druzgala: Compounds for treatment of cardiac arrhythmia, synthesis, and methods of use. ARYx Therapeutics, McDonnell Boehnen Hulbert & Berghoff, March 22, 2005: US06869972 (1 worldwide citation)

The subject invention pertains to novel compounds (and salts thereof), and compositions comprising the compounds, for the treatment of cardiac arrhythmias. The subject invention further concerns methods of making the novel compounds. The novel compounds are rapidly metabolized analogs of amiodarone, ...


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Stuart E Bradley, Eric W Collington, Matthew C Fyfe, Martin J Procter, Colin P Sambrook Smith: Resorcinol derivatives. Pfizer, Roseanne Goodman, February 8, 2005: US06852747 (1 worldwide citation)

The present invention relates to certain resorcinol derivatives and their use as skin lightening agents.


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