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Mohamed SKIBA Mohamed SKIBA
Mohamed Skiba, Denis Wouessidjewe, Hatem Fessi, Jean Philippe Devissaguet, Dominique Duchene, Francis Puisieux: Preparation and use of novel cyclodextrin-based dispersible nanovesicular colloidal systems in the form of nanocapsules. Centre Nat Rech Scient, December 17, 1993: FR2692167-A1 (1 worldwide citation)

A nanovesicular system prepared by (1) preparing a liquid phase essentially consisting of a solution of cyclodextrin modified by acyl groups, and an oil in an organic solvent or solvent mixture; (2) preparing a second liquid phase essentially consisting of water or an aqueous mixture optionally cont ...


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Mohamed SKIBA Mohamed SKIBA
Mohamed Skiba, Denis Wouessidjewe, Antony Coleman, Hatem Fessi, Jean Philippe Devissaguet, Dominique Duchene, Francis Puisieux: Preparation and use of novel cyclodextrin-based dispersible colloidal systems in the form of nanospheres. Centre Nat Rech Scient, December 17, 1993: FR2692168-A1

A nanoparticulate system prepared by: 1) preparing a liquid phase essentially consisting of a solution of cyclodextrin modified by acyl groups in an organic solvent or solvent mixture, an active molecule being optionally added thereto; 2) preparing a second liquid phase essentially consisting of wat ...


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Ronald J Tuch: Intravascular stent and method. Medtronic, Daniel W Latham, Harold R Patton, October 21, 1997: US05679400 (533 worldwide citation)

A method for making an intravascular stent by applying to the body of a stent a solution which includes a solvent, a polymer dissolved in the solvent and a therapeutic substance dispersed in the solvent and then evaporating the solvent. The inclusion of a polymer in intimate contact with a drug on t ...


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Pieter Bonsen, Patrick S Wong, Felix Theeuwes: Method of delivering drug with aid of effervescent activity generated in environment of use. Alza Corporation, Paul L Sabatine, Edward L Mandell, Thomas E Ciotti, May 5, 1981: US04265874 (404 worldwide citation)

A method is disclosed for delivering a drug substantially free of rapid precipitation from an osmotic device. The osmotic device comprises a semipermeable wall surrounding a compartment, housing (1) a drug that exhibits limited solubility under neutral and acid conditions; and (2) a compound capable ...


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James H Brauker, Ronald S Hill, Laura A Martinson, Daniel R Boggs, Robert C Johnson: Tissue inplant systems and methods for sustaining viable high cell densities within a host. Baxter International, Sarah E Bates, Daniel D Ryan, Paul C Flattery, May 24, 1994: US05314471 (378 worldwide citation)

Implant assemblies and methodologies provide immuno-protection for implanted allografts, xenografts, and isografts. The assemblies and methodologies establish a boundary between the host and the implanted cells. The boundary has a pore size, an ultimate strength, and a metabolic transit value that a ...


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Anthony M Albisser, Bernard S Leibel: Artificial beta cell. Hospital for Sick Children, Hirons Rogers & Scott, January 20, 1981: US04245634 (360 worldwide citation)

An artificial beta cell regulates blood glucose concentration in a subject by continuously analyzing blood from the patient and deriving a computer output signal to drive a pump which infuses insulin at a rate corresponding to the signal. A value of blood glucose concentration from the analyzed bloo ...


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Solomon Steiner, Robert Rosen: Delivery systems for pharmacological agents encapsulated with proteinoids. Clinical Technologies Associates, Kilpatrick & Cody, May 15, 1990: US04925673 (342 worldwide citation)

Methods are described for targeting the release of an active pharmacological agent in an animal by administering that agent encapsulated in proteinoid microspheres which are stable to the environment encountered from the point of introduction until they migrate to the targeted body organs, fluids or ...


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Klefstad Sillonville Francis: Remote medical aid and monitoring system. Klefstad Sillonville Francis, September 25, 1998: FR2760962-A1 (294 worldwide citation)

The system consists of sets of apparatus (10) for automatically recording patients' physiological parameters, and connectors (12) linking them to an information feeder (14) by a data transmission network (16,18). The apparatus or connectors incorporate memories which are programmable from informatio ...



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