1
J Christopher Flaherty, Joshua Makower, Philip C Evard, Patrick E MacAulay, Jason B Whitt, Robert C Colloton, K Angela Macfarlane: Systems and methods for delivering drugs to selected locations within the body. Transvascular, William A English, Cohen and Sakaguchi, February 3, 2004: US06685648 (406 worldwide citation)

A method is provided for delivering a drug to a selected tissue region within a patient's body with a catheter having a deployable puncturing element, a drug delivery element and an orientation element on a distal portion thereof. The distal portion of the catheter is percutaneously introduced ...


2
Michael V Scanlon: Acoustic monitoring system. The United States of America represented by the Secretary of the Army, Paul S Clohan Jr, William Eshelman, Mark Kelly, December 29, 1998: US05853005 (342 worldwide citation)

A transducer in communication with fluid in a pad held in close contact against a sound or movement source monitors acoustic signals transferred into the fluid. The signal pattern is monitored aurally and/or compared to predetermined reference patterns, and optional control and stimulation means can ...


3
Assaf Govari, Maier Fenster: Pressure-sensing stent. Biosense, Paul A Coletti, Louis J Capezzuto, April 25, 2000: US06053873 (307 worldwide citation)

Implantable apparatus for measuring a fluid flow in the body of a subject, including a stent, having a generally cylindrical radial outer wall and a central lumen. A flow parameter sensor is fixed to the stent, and measures a parameter relating to a rate of blood flow through the stent. A transmitte ...


4
Michel Schneider, Daniel Bichon, Philippe Bussat, Jerome Puginier, Eva Hybl Sutherland: Stable microbubbles suspensions injectable into living organisms. Bracco International, Nixon & Vanderhye, January 10, 1995: US05380519 (202 worldwide citation)

Gas or air filled microbubble suspensions in aqueous phase usable as imaging contrast agents in ultrasonic echography. They contain laminarized surfactants and, optionally, hydrophilic stabilizers. The laminarized surfactants can be in the form of liposomes. The suspensions are obtained by exposing ...


5
James J Leary, John R McKenzie: Ultrasonic imaging catheter with guidewire channel. Cardiovascular Imaging Systems, Townsend and Townsend, June 18, 1991: US05024234 (199 worldwide citation)

Intravascular catheters including both a flexible catheter body and a less flexible housing mounted at a distal end of the catheter body are provided with a flexible distal tip, preferably having a conical geometry. Guidewire channel or lumen is formed within the tip, and optionally additional guide ...


6
Guido P M Prause, Milan Sonka: Apparatus and method for determining three-dimensional representations of tortuous vessels. University of Iowa Research Foundation, Fleshner & Kim, November 14, 2000: US06148095 (179 worldwide citation)

Three-dimensional reconstructions of tortuous vessels such as coronary arteries can be obtained by data fusion between biplane angiography and IVUS frames of a pullback sequence. The 3D course of the tortuous vessel is first determined from the angiograms and then combined with the 2D representation ...


7
Wayne Sieben, Mark J Whalen: Intravascular imaging apparatus and methods for use and manufacture. Scimed Life Systems, Willian Brinks Olds Hofer Gilson & Lione, September 14, 1993: US05243988 (167 worldwide citation)

A device for ultrasonic imaging, and methods for the use an manufacture thereof, particularly of small coronary vessels. The device comprises an elongate member with a distal end that can be positioned within a small vessel of a patient's body while a proximal end is located outside the body, a tran ...


8
Shih Ping Wang, Shengtz Lin, Siqing Zhang, Donald Chin, Karen D Maroc: Guide and position monitor for invasive medical instrument. U Systems, Cooper & Dunham, February 24, 2004: US06695786 (153 worldwide citation)

An instrument guide is described for mounting an invasive instrument such as a biopsy needle to an imaging probe, controlling its position, monitoring its position, and/or predictively displaying its position on a user display of the medical imaging system. A plurality of substantially rigid segment ...


9
Lloyd K Willard, Mark Whalen, Wayne Sieben: Sheath for selective delivery of multiple intravascular devices and methods of use thereof. Lyon & Lyon, October 30, 2001: US06309379 (149 worldwide citation)

An intravascular device, such as a sheath, and methods for use thereof for selective alternate positioning of other intravascular devices having predetermined sizes in a distal vascular region of the body of a patient. The intravascular selection sheath comprises a tubular body having proximal, inte ...


10
Robert A Rabiner, Bradley A Hare: Ultrasonic device for tissue ablation and sheath for use therewith. OmniSonics Medical Technologies, Fish & Richardson P C, March 17, 2009: US07503895 (148 worldwide citation)

A transverse mode ultrasonic probe is provided which creates a cavitation area along its longitudinal length, increasing the working surface of the probe. Accessory sheaths are also provided for use with the probe to enable a user to select from features most suited to an individual medical procedur ...