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LIU Xuedong, PHILLIPS Andrew J, UNGERMANNOVA Dana, NASVESCHUK Christopher G, ZHANG Gan: Composés macrocycliques utiles comme inhibiteurs des histones déacétylases, Macrocyclic compounds useful as inhibitors of histone deacetylases. The Regents Of The University Of Colorado, LIU Xuedong, PHILLIPS Andrew J, UNGERMANNOVA Dana, NASVESCHUK Christopher G, ZHANG Gan, Swanson & Bratschun L L C, December 1, 2011: WO/2011/150283 (1 worldwide citation)

The present invention provides a novel macrocyclic compound of general Formula (I) having histone deacetylase (HDAC) inhibitory activity, a pharmaceutical composition comprising the compound, and a method useful to treat diseases using the compound.


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SU Tin Tin, ZHANG Gan, GLADSTONE Mara N: ENTITÉS CHIMIQUES ET LEURS UTILISATIONS THÉRAPEUTIQUES, CHEMICAL ENTITIES AND THERAPEUTIC USES THEREOF. REGENTS OF THE UNIVERSITY OF COLORADO A BODY CORPORATE, SU Tin Tin, ZHANG Gan, GLADSTONE Mara N, HUANG Tao, June 7, 2012: WO/2012/075472 (1 worldwide citation)

The present invention describes the use of translation inhibitors for the treatment of cancer and other disorders. Described herein are translation-inhibiting compounds, and methods of using those compounds for the treatment of cancer and other disorders. In some aspects the compounds inhibit transl ...


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Hsu Kuo Chuan, Zhang Gan Cheng, Tseng Chien Liang, Zhang Zheng Li: Li2o-al2o3-sio2 crystalline glass and crystallized glass and manufacturing method of li2o-al2o3-sio2 crystallized glass. Huzhou Daikyo Hari Seihin Yugenkoshi, August 3, 2006: JP2006-199538 (1 worldwide citation)

PROBLEM TO BE SOLVED: To provide an Li2O-Al2O3-SiO2 crystalline glass, and a crystallized glass which is excellent in thermal characteristics and mechanical strength and can be manufactured through nucleus formation in the crystalline glass and subsequent crystallization at a relatively low temperat ...


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HAAS JULIA , ANDREWS STEVEN W , JIANG YUTONG , ZHANG GAN : [de] SUBSTITUIERTE PYRAZOLO[1,5-A]PYRIMIDIN-VERBINDUNGEN ALS TRK-KINASEHEMMERN, [en] SUBSTITUTED PYRAZOLO[1,5-]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS, [fr] PYRAZOLO [1,5-] PYRIMIDINE EN TANT QUINHIBITEURS DE KINASES TRK. ARRAY BIOPHARMA  , December 21, 2016: EP3106463-A1

[en] Compounds of Formula (I) in which R 1 , R 2 , R 3 , R 4 , X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor.


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Zhang Gan: Method and equipment for cultivating or raising fry of sea livings with increased pressure. Zhang Gan, September 9, 1998: CN97101381

A method and equipment with a pressure controll system for growing seedlings and breeding marine living beings regulates the water pressure to make the artificial breeding condition simulating the natural sea condition. The main equipments is composed of pressure control system, breeding water suppl ...


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Mg Kelly, Zhang Gan: Arylpiperidine and aryl-1,2,5,6-tetrahydropyridine urea derivatives having 5ht1a receptor activity. American Home Products Corporation, guan lixin, February 13, 2002: CN99814560

Compounds of formula (A) are useful for the treatment of disorder of the central nervous system including anxiety, depression, panic, alcohol and drug addiction, sexual dysfunction, sleep disorders, migraine, obesity, cognitive disorders and neurodegenerative diseases.