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Miesenbock Gero A, Zemelman Boris V: Heterologous stimulus-gated ion channels and methods of using same. Sloan Kettering Institute For Cancer Research, Miesenbock Gero A, Zemelman Boris V, LARSON Marina T, December 11, 2003: WO/2003/102156 (10 worldwide citation)

Methods and compositions to activate a genetically designated target cell (or population of targetcells) artificially, in vivo or in vitro, employ triggering of heterologous stimulus-gated ion channels to activate the cells. The stimulus-gated ion channels are suitably TRPV1, TRPM8 or P2X2. A stimul ...


2
Miesenbock Gero, Zemelman Boris: Bio-synthetic photostimulators and methods of use. Sloan Kettering Institute For Cancer Research, ADLER Benjamin A, February 27, 2003: WO/2003/016486 (8 worldwide citation)

Method for rendering a cell sensitive to stimulation. In a preferred embodiment, the method comprises introducing, into a cell, nucleic acid sequences encoding at least an opsin gene product, an arrestin gene product, and the alpha subunit of the heterotrimeric G protein of the G¿q? family. The intr ...


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Miesenbock Gero A, Zemelman Boris V: Heterologous stimulus-gated ion channels and methods of using same. Sloan Kettering Institutefor C, May 25, 2005: EP1532452-A2

Methods and compositions to activate a genetically designated target cell (or population of targetcells) artificially, in vivo or in vitro, employ triggering of heterologous stimulus-gated ion channels to activate the cells. The stimulus-gated ion channels are suitably TRPV1, TRPM8 or P2X2. A stimul ...


4
Miesenbock Gero A, Zemelman Boris V: Heterologous stimulus-gated ion channels and methods of using same. Sloan Kettering Inst Cancer, wang jingchao, September 21, 2005: CN03817754

Methods and compositions to activate a genetically designated target cell (or population of targetcells) artificially, in vivo or in vitro, employ triggering of heterologous stimulus-gated ion channels to activate the cells. The stimulus-gated ion channels are suitably TRPV1, TRPM8 or P2X2. A stimul ...