1
Zamboni Robert, Prasit Petpiboon, Young Robert N: Quinoline ether alkanoic acid.. Merck Frosst Canada, January 3, 1990: EP0349062-A1 (57 worldwide citation)

Compounds having the formula: are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, ...


2
Young Robert N, Zamboni Robert, Williams Haydn W R, Belley Michel L: Quinoline dioic acids and amides.. Merck Frosst Canada, June 15, 1988: EP0271287-A2 (55 worldwide citation)

Compounds having the formula are antagonists of leukotrienes and inhibitors of their biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.


3
Young Robert N, Leger Serge, Frenette Richard, Zamboni Robert, Williams Hayden W R: 2-substituted quinolines, their preparation and use.. Merck Frosst Canada, December 30, 1986: EP0206751-A2 (42 worldwide citation)

Compounds having the formula: are selective antagonists of leukotrienes of D4. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents and may be made up into pharmaceutical compositions. In the formula R is H, halogen, C1-C8 alkyl, C2-C8 alkenyl, C2 ...


4
Young Robert N, Zamboni Robert, Leger Serge: 2-substituted quinoline dioic acids.. Merck Frosst Canada, August 26, 1987: EP0233763-A2 (26 worldwide citation)

Compounds having the formula: are antagonists of leukotrienes and inhibitors of their biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.


5
Vohra Rahul, Babinski Kazimierz, Brochu Jean Louis, Ntirampebura Deogratias, Wei Chang Qing, Zamboni Robert Joseph, Reayi Ayub A: Compositions and methods for modulating gated ion channels. Painceptor Pharma Corporation, Vohra Rahul, Babinski Kazimierz, Brochu Jean Louis, Ntirampebura Deogratias, Wei Chang Qing, Zamboni Robert Joseph, Reayi Ayub A, BARRANS J David, June 28, 2007: WO/2007/071055 (26 worldwide citation)

Disclosed are quinoline and quinazoline compounds which modulate the activity of the gated ion channels. Compounds that modulate these gated ion channels are useful in the treatment of diseases and disorders related to pain, inflammation, the neurological system, the gastrointestinal system and geni ...


6
Young Robert N, Gauthier Jacques Yves, Zamboni Robert, Belley Michel L: Diarylstyrylquinoline diacids.. Merck Frosst Canada, November 28, 1990: EP0399818-A1 (22 worldwide citation)

Compounds having the formula: are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.


7
Young Robert N, Zamboni Robert, Leger Serge: 2-substituted quinolines.. Merck Frosst Canada, April 22, 1987: EP0219308-A2 (18 worldwide citation)

Novel compounds have the formula: or are pharmaceutically acceptable salts thereof. In the formula: Y is -(CR=CR)n-, -(C IDENTICAL C)n-, -CRR-X-, -X-CRR-, -CRR-X-CRR-, X, C=O, -NR- @-, or -@-NR-; R is H, halogen, C1-8 alkyl, C2-8 alkenyl, C2-8 alkynyl, -CF3, -OR, -SR, -SOR, -SO2R, -NRR, -CHO, -COOR, ...


8
Young Robert N, Zamboni Robert: Benzoheterazoles.. Merck Frosst Canada, May 31, 1989: EP0318084-A2 (16 worldwide citation)

Compounds having the formula: are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, antiallergic, anti-inflammatory, and cytoprotective agents.


9
Young Robert N, Zamboni Robert, Gauthier Jacques Y, Belley Michel L: Diarylquinoline diacids and their use as medicaments.. Merck Frosst Canada, May 31, 1989: EP0318093-A2 (14 worldwide citation)

Compounds having the formula: are leukotriene antagonists and nhibtors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic anti-allergic, anti-inflammatory and cytoprotective agents.


10
Young Robert N, Zamboni Robert, Gauthier Jacques Y: Pyridyl dialkanoic acids and their use as medicaments.. Merck Frosst Canada, May 31, 1989: EP0318083-A2 (11 worldwide citation)

Compounds having the formula. are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.