1
Dario Cabib, Robert A Buckwald, Zvi Malik, Yuval Garini, Nir Katzir, Dirk G Soeknsen: Spectral bio-imaging methods for biological research, medical diagnostics and therapy. Applied Spectral Imaging, Mark M Friedman, July 21, 1998: US05784162 (283 worldwide citation)

According to the present invention there are provided spectral imaging methods for biological research, medical diagnostics and therapy comprising the steps of (a) preparing a sample to be spectrally imaged; (b) viewing the sample through an optical device, the optical device being optically connect ...


2
Dirk C Soenksen, George McNamara, Yuval Garini, Nir Katzir: Method of cancer cell detection. Applied Spectral Imaging, Mark M Friedman, November 30, 1999: US05995645 (104 worldwide citation)

A method for cancer cell detection including the steps of (a) staining an analyzed sample with at least first and second dyes, the dyes being selected such that the first dye better adheres to normal cells whereas the second dye better adheres to cancer cells; (b) spectrally imaging the sample throu ...


3
Yuval Garini, Dario Cabib, Robert A Buckwald, Thomas Ried, Dirk G Soenksen: Method for simultaneous detection of multiple fluorophores for in situ hybridization and multicolor chromosome painting and banding. Applied Spectral Imaging, Mark M Friedman, May 23, 2000: US06066459 (93 worldwide citation)

A spectral imaging method for simultaneous detection of multiple fluorophores aimed at detecting and analyzing fluorescent in situ hybridizations employing numerous chromosome paints and/or loci specific probes each labeled with a different fluorophore or a combination of fluorophores for color kary ...


4
Yuval Garini, George McNamara, Dirk Soenksen, Dario Cabib, Robert A Buckwald: In-situ method of analyzing cells. Applied Spectral Imaging, December 26, 2000: US06165734 (82 worldwide citation)

A method of in situ analysis of a biological sample comprising the steps of (a) staining the biological sample with N stains of which a first stain is selected from the group consisting of a first immunohistochemical stain, a first histological stain and a first DNA ploidy stain, and a second stain ...


5
Yuval Garini, Dario Cabib, Robert A Buckwald, Thomas Ried, Dirk G Soenksen: Method for simultaneous detection of multiple fluorophores for in situ hybridization and multicolor chromosome painting and banding. Applied Spectral Imaging, Mark M Friedman, October 6, 1998: US05817462 (56 worldwide citation)

A spectral imaging method for simultaneous detection of multiple fluorophores aimed at detecting and analyzing fluorescent in situ hybridizations employing numerous chromosome paints and/or loci specific probes each labeled with a different fluorophore or a combination of fluorophores for color kary ...


6
Yuval Garini, Dario Cabib, Robert A Buckwald, Dirk G Soenksen, Nir Katzir, David Wine, Moshe Lavi: Color display of chromosomes or portions of chromosomes. Applied Spectral Imaging, Mark M Friedman, April 25, 2000: US06055325 (39 worldwide citation)

A color display comprising an image of all chromosomes or portions of chromosomes of a cell, each of the chromosomes or portions of chromosomes being painted with a different fluorophore or a combination of fluorophores, the image presenting the chromosomes or portions of chromosomes in different di ...


7
Nir Katzir, David Wine, Yuval Garini, Dario Cabib: Method for classification of pixels into groups according to their spectra using a plurality of wide band filters and hardwire therefore. Applied Spectral Imaging, Mark M Friedman, November 10, 1998: US05834203 (38 worldwide citation)

A method of classification of pixels into groups of pixels according to their association with a single fluorophore or a combination of fluorophores selected from a plurality of fluorophores, each of the fluorophores having characterizing excitation and emission spectra and specifying excitation and ...


8
Yuval Garini, Nir Katzir, David Wine, Dario Cabib: Method for chromosomes classification. Applied Spectral Imaging, August 25, 1998: US05798262 (30 worldwide citation)

A method for finding L internal reference vectors for classification of L chromosomes or portions of chromosomes of a cell, the L chromosomes or portions of chromosomes being painted with K different fluorophores or combinations thereof, wherein K basic chromosomes or portions of chromosomes of the ...


9
Dario Cabib, Robert A Buckwald, David Wine, Yuval Garini, Nir Katzir, Dirk G Soeknsen, Moshe Lavi: Method for simultaneous detection of multiple fluorophores for in situ hybridization and chromosome painting. Applied Spectral Imaging, Mark M Friedman, August 10, 1999: US05936731 (27 worldwide citation)

A fluorescent in situ hybridization method comprising the steps of (a) providing a cell nuclei having chromosomes hybridized with at least one nucleic acid probe including at least one nucleic acid molecule labeled with at least one fluorophore; (b) viewing the cell nuclei through a fluorescence mic ...


10
Yuval Garini, Nir Katzir, David Wine, Dario Cabib: Method for chromosomes classification. Applied Spectral Imaging, Mark M Friedman, May 25, 1999: US05906919 (18 worldwide citation)

A method for finding L internal reference vectors for classification of L chromosomes or portions of chromosomes of a cell, the L chromosomes or portions of chromosomes being painted with K different fluorophores or combinations thereof, wherein K basic chromosomes or portions of chromosomes of the ...