1
Masanori Oka, Shokyu Gen, Yoshito Ikada, Hideaki Okimatsu: Artificial intervertebral disc. Kyocera Corporation, Kabushiki Kaisha Biomaterial Universe Corporation of Japan, Spensley Horn Jubas & Lubitz, October 17, 1995: US05458643 (467 worldwide citation)

A prosthesis used for a damaged bone, an artificial articular cartilage or an artificial intervertebral disc being characterized in that the prosthesis is a composite body comprising polyvinyl alcohol hydrogel and ceramic or metallic porous body. With this prosthesis, PVA hydrogel enhances lubricati ...


2
Suong Hyu Hyon, Yoshito Ikada: Porous and transparent poly(vinyl alcohol) gel and method of manufacturing the same. Biomaterials Universe, Antonelli Terry & Wands, May 5, 1987: US04663358 (298 worldwide citation)

A porous and transparent hydrated gel is prepared from a poly(vinyl alcohol) solution in a mixed solvent consisting of water and an water-miscible organic solvent. Upon cooling the poly(vinyl alcohol) solution below room temperature, a gel is formed as a consequence of crystallization of poly(vinyl ...


3
Masanori Oka, Shokyu Gen, Yoshito Ikada, Hideaki Okimatsu: Artificial bone connection prosthesis. Kyocera Corporation, Kabushiki Kaisha Biomaterial Universe, Spensley Horn Jubas & Lubitz, May 24, 1994: US05314478 (290 worldwide citation)

A prosthesis used for a damaged bone, an artificial articular cartilage or an artificial intervertebral disc being characterized in that the prosthesis is a composite body comprising polyvinyl alcohol hydrogel and ceramic or metallic porous body. With this prosthesis, PVA hydrogel enhances lubricati ...


4
Masao Okada, Kazuhiko Sakai, Haruo Kimura, Yoshito Ikada: Method for manufacturing a synthetic vascular prosthesis. Ube Nitto Kasei, Research Development Corporation of Japan, Japan Medical Supply, Wenderoth Lind & Ponack, July 17, 1990: US04941870 (257 worldwide citation)

A synthetic vascular prosthesis comprises a hollow tubular base member having a multitude of continuous pores and formed of an elastomer material, and a hydrogel layer formed on the inner surface of the base member. The hydrogel layer is partly embedded in the inner portion of the base member at the ...


5
Yuichiro Ogura, Yoshito Ikada: Biodegradable scleral plug. Santen Pharmaceutical, Frishauf Holtz Goodman Langer & Chick P C, January 13, 1998: US05707643 (171 worldwide citation)

The present invention relates to a scleral plug made of lactic acid copolymer; a scleral plug containing a drug that is designed to gradually release the drug into a vitreous body; and a scleral plug that is used to treat or prevent diseases of the retina or to promote recovery from damage after vit ...


6
Hajime Handa, Yasuhiro Yonekawa, Sen Yamagata, Waro Taki, Yoshito Ikada, Hiroo Iwata: Releasable balloon catheter. Kuraray, Oblon Fisher Spivak McClelland & Maier, September 6, 1983: US04402319 (149 worldwide citation)

This invention provides a releasable balloon catheter having a portion cuttable by torsion or a portion cuttable by heating at or near a joint part between the catheter body and the balloon. When the balloon catheter is inserted into a vessel and carried to the desired site by the blood stream and t ...


7
Yoshito Ikada, Hyu H Suong, Yoshihiko Shimizu, Satoshi Watanabe, Tatsuo Nakamura, Masakazu Suzuki, Takeshi Shimamoto: Osteosynthetic pin. Gunze, Armstrong Nikaido Marmelstein Kubovcik & Murray, February 6, 1990: US04898186 (134 worldwide citation)

An osteosynthetic pin characterized in that the pin is formed substantially of a poly-L-lactic acid having a molecular weight of at least about 70,000, and is formed by axially drawing about 2 to about 10 times at an elevated temperature of about 70.degree. to about 120.degree. C.


8
Hajime Handa, Yasuhiro Yonekawa, Sen Yamagata, Waro Taki, Yoshito Ikada, Hiroo Iwata: Releasable balloon catheter. Kuraray Company, Oblon Fisher Spivak McClelland & Maier, August 31, 1982: US04346712 (124 worldwide citation)

This invention provides a releasable balloon catheter having a tube cuttable by torsion or a tube cuttable by heating at a joint part between the catheter body and the balloon. When the balloon catheter is inserted into a vessel and carried to the desired site by the blood stream and the balloon is ...


9
Suong Hyu Hyon, Yoshito Ikada: Method of molding a polyvinyl alcohol contact lens. Biomaterials Universe, Armstrong Nikaido Marmelstein Kubovcik & Murray, October 17, 1989: US04874562 (92 worldwide citation)

A soft contact lens of PVA having a tensile strength of not less than 10 kg/cm.sup.2, a water content ranging from 40 to 95% by weight, a visible light transparency of not less than 90%, and an oxygen permeability of not less than 30.times.10.sup.-11 cm.sup.3.(STP).cm/cm.sup.2.sec.mmHg. This soft co ...


10
Hajime Handa, Yasuhiro Yonekawa, Sen Yamagata, Waro Taki, Yoshito Ikada, Hiroo Iwata: Balloon catheter. Kuraray, Oblon Fisher Spivak McClelland & Maier, November 24, 1981: US04301803 (82 worldwide citation)

Disclosed is a balloon catheter including a catheter and a balloon bonded to the catheter through an adhesive in which the outer surface of the balloon is contiguous to the outer surface of the catheter through a smooth surface. In this balloon catheter, the balloon is tightly fixed to the catheter ...