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Teruo Hiruma, Atsushi Honma, Tooru Hirano, Yutaka Tsuchiya, Yoshihiro Hayata, Katsuo Aizawa, Harubumi Kato, Keiji Kainuma: Cancer diagnosis device utilizing laser beam pulses. Hamamatsu TV, Spencer & Frank, December 3, 1985: US04556057 (152 worldwide citation)

Cancer diagnosis device contains an endoscope comprising a light pipe used to transmit light beams from respective light sources and an image guide used to observe the flesh of the organism during both diagnosis and treatment. The tip of the endoscope faces toward the focuses where a photosensitive ...


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Makoto Kaneda, Yoshihiro Fujii, Yoshihiro Hayata, Yoshiro Kishi, Ichiro Yahara: Antibody being capable of binding to transforming growth factor alpha and having growth-suppressing activity on cancers having Ras gene mutation. Medical & Biological Laboratories, Sughrue Mion PLLC, March 17, 2015: US08980257

It has been found out that among antibodies showing reactivity with wild type TGF-α, antibodies less reactive with G79A-substituted TGF-α have an excellent growth-suppressing effect on cancer cells having a mutated Ras gene. Further, it has been found out that most of these antibodies have an activi ...