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Mathai Mammen, Yu Hua Ji, YongQi Mu, Craig Husfeld, Li Li: Biphenyl compounds useful as muscarinic receptor antagonists. Theravance, Jeffrey A Hagenah, Shelley Eberle, October 30, 2007: US07288657 (34 worldwide citation)

This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, W, Ar1, R1, R2, R3, R4, R6, R7, and R8 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compo ...


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Mathai Mammen, Yu Hua Ji, YongQi Mu, Craig Husfeld, Li Li: Biphenyl compounds useful as muscarinic receptor antagonists. Theravance, Jeffrey A Hagenah, Shelley Eberle, September 4, 2007: US07265133 (30 worldwide citation)

This invention provides compounds of formula I: wherein a, b, c, m, p, s, t, W, Ar1, X1, R1, R2, R3, R4, R6, and R7 are as defined specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, process ...


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Mathai Mammen, Yu Hua Ji, YongQi Mu, Eric L Stangeland, Aaron Kushner, Craig Husfeld: Biphenyl compounds useful as muscarinic receptor antagonists. Theravance, Jeffrey A Hagenah, Shelley Eberle, August 28, 2007: US07262205 (27 worldwide citation)

This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, r, R1, R2, R3, R4, R5, R6, R7, and W are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, pr ...


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Yu Hua Ji, Craig Husfeld, Mathai Mammen, YongQi Mu, Eric L Stangeland: Biphenyl compounds useful as muscarinic receptor antagonists. Theravance, Jeffrey A Hagenah, Shelley Eberle, January 20, 2009: US07479562 (23 worldwide citation)

The invention provides compounds of formula I: wherein a, b, c, d, f, W, Q, Y, R1, R2, and R3 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermed ...


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Mathai Mammen, Yu Hua Ji, YongQi Mu, Trevor Mischki, Viengkham Malathong: Biphenyl compounds useful as muscarinic receptor antagonists. Theravance, Jeffrey A Hagenah, Shelley Eberle, November 25, 2008: US07456199 (22 worldwide citation)

This invention provides compounds of formula I: wherein a, b, c, m, p, s, t, W, Ar1, X1, R1, R2, R3, R4, R6, and R7 are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, ...


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Mathai Mammen, Yu Hua Ji, YongQi Mu: Biphenyl compounds useful as muscarinic receptor antagonists. Theravance, Jeffrey A Hagenah, Shelley Eberle, July 14, 2009: US07560469 (21 worldwide citation)

This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, s, t, Ar1, R1, R2, R3, R4, R6, R7, R8, and W are as defined in the specification. The compounds of formula I are mescaline receptor antagonists. The invention also provides pharmaceutical compositions containing such compou ...


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Mathai Mammen, Yu Hua Ji, YongQi Mu: Biphenyl compounds useful as muscarinic receptor antagonists. Theravance, Jeffrey A Hagenah, Shelley Eberle, April 28, 2009: US07524962 (21 worldwide citation)

This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, r, R1, R2, R3, R4, R5, R6, R7, and W are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, pr ...


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J Kevin Judice, Jeng Pyng Shaw, YongQi Mu, Michael W Conner, John L Pace: Pharmaceutical compositions containing a glycopeptide antibiotic and a cyclodextrin. Theravance, Jeffrey A Hagenah, April 11, 2006: US07026288 (19 worldwide citation)

Disclosed are pharmaceutical compositions containing a cyclodextrin and a therapeutically effective amount of a glycopeptide antibiotic or a salt thereof. Also disclosed are methods of treating a bacterial disease in a mammal by administering such pharmaceutical compositions.


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