1
Stephen D Pacetti, Yiwen Tang: Stent coatings comprising hydrophilic additives. Advanced Cardiovascular Systems, Squire Sanders & Dempsey L, October 9, 2007: US07279174 (120 worldwide citation)

A coating for implantable medical devices and a method for fabricating thereof are disclosed. The coating includes a mixture of a hydrophobic polymer and a polymeric hydrophilic additive, wherein the hydrophobic polymer and the hydrophilic additive form a physically entangled or interpenetrating sys ...


2
Syed F A Hossainy, Yiwen Tang, Andrew C Tung, Stephen D Pacetti: Method for fabricating a coating for a medical device. Advanced Cardiovascular Systems, Squire Sanders & Dempsey L, August 9, 2005: US06926919 (76 worldwide citation)

Methods for fabricating coatings for implantable medical devices are disclosed. The coatings include blends of hydrophilic and hydrophobic polymers. The methods provide for treatment of the coatings to cause enrichment a region close to the outer surface of the coating with the hydrophilic polymers.


3
Syed F A Hossainy, Eugene T Michal, Yiwen Tang: Biologically absorbable coatings for implantable devices and methods for fabricating the same. Advanced Cardiovasular Systems, Squire Sanders & Dempsey L, January 30, 2007: US07169404 (36 worldwide citation)

Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.


4
Syed F A Hossainy, Yiwen Tang, Andrew C Tung, Stephen D Pacetti: Stent coating. Advanced Cardiovascular Systems, Squire Sanders & Dempsey L, June 20, 2006: US07063884 (34 worldwide citation)

A stent comprising a coating layer is disclosed. The coating layer has a hydrophobic component and a hydrophilic component, wherein a region of the coating layer on or about the outermost surface of the coating layer has a higher content or concentration of the hydrophilic component than the hydroph ...


5
Syed F A Hossainy, Yiwen Tang, Gina Zhang: Polyactive/polylactic acid coatings for an implantable device. Advanced Cardiovascular Systems, Squire Sanders & Dempsey, December 25, 2007: US07311980 (33 worldwide citation)

A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided.


6
Stephen D Pacetti, Syed F A Hossainy, Yiwen Tang, Andrew C Tung, Thierry Glauser: Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof. Advanced Cardiovascular Systems, Squire Sanders & Dempsey, February 12, 2008: US07329413 (24 worldwide citation)

Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer.


7
Stephen D Pacetti, Yiwen Tang: Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same. Advanced Cardiovascular Systems, Squire Sanders & Dempsey L, May 8, 2007: US07214759 (23 worldwide citation)

Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction c ...


8
Jessica Renee DesNoyer, Stephen Dirk Pacetti, Syed Faiyaz Shmed Hossainy, Lothar Kleiner, Yiwen Tang, Gina Zhang: Poly(ester amide) filler blends for modulation of coating properties. Advanced Cardiovascular Systems, Squire Sanders & Dempsey, June 24, 2008: US07390497 (18 worldwide citation)

Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom. The PEA polymer blend is formed of a PEA polymer and a material capable of hydrogen bonding with the PEA. The PEA polymer blend can form a coating on an implantable device, one example of which is a stent. T ...


9
Syed F A Hossainy, Yiwen Tang, Manish Gada: Thermal treatment of an implantable medical device. Advanced Cardiovascular Systems, Squire Sanders & Dempsey L, October 5, 2010: US07807211 (17 worldwide citation)

A method of manufacturing an implantable medical device, such as a drug eluting stent, is disclosed. The method includes subjecting an implantable medical device that includes a polymer to a thermal condition. The thermal condition can result in reduction of the rate of release of an active agent fr ...


10
Syed Faiyaz Ahmed Hossainy, Yiwen Tang, Lothar W Kleiner: Medical device coated with a coating containing elastin pentapeptide VGVPG. Abbott Cardiovascular Systems, Squire Sanders & Dempsey, October 4, 2011: US08029816 (16 worldwide citation)

The present invention is directed to medical devices including coatings. The coatings include a topcoat which includes a copolymer comprising a block of an elastin pentapeptide. The topcoat is over a layer of poly(vinyl alcohol) on a hydrophobic coating or over a porous coating comprising pores or d ...