1
Theodore Karwoski, Yasuo Matsuzawa: Vascular prosthesis having fluorinated coating with varying F/C ratio. Atrium Medical Corporation, Lahive & Cockfield, January 12, 1988: US04718907 (358 worldwide citation)

Disclosed is a method of producing implantable prosthetic devices, e.g., tubular vascular prostheses having a substantially non-thrombogenic inside surface and a biocompatible outside surface. The method involves deposition onto an elongate substrate, e.g., a porous tubular substrate, of a fluorine- ...


2
Theodore Karwoski, Yasuo Matsuzawa: Glow discharge process for producing implantable devices. Atrium Medical Corporation, Lahive & Cockfield, December 30, 1986: US04632842 (123 worldwide citation)

Disclosed is a method of producing implantable prosthetic devices, e.g., tubular vascular prostheses having a substantially non-thrombogenic inside surface and a biocompatible outside surface. The method involves deposition onto an elongate substrate, e.g., a porous tubular substrate, of a fluorine- ...


3
Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Yasuo Matsuzawa: Method for applying an LbL coating onto a medical device. Novartis, Jian Zhou, Robert Gorman, R Scott Meece, May 24, 2005: US06896926 (83 worldwide citation)

The present invention provides an improved LbL-coating process for modifying the surface of a medical device, preferably an ophthalmic device, more preferably a contact lens. An LbL coating on a contact lens, which is prepared according to the process of the invention, can have increased hydrophilic ...


4
Yasuo Matsuzawa, Lynn Cook Winterton: Lens plasma coating system. Novartis, July 18, 2006: US07078074 (17 worldwide citation)

The invention provides a method for plasma coating of optical lenses, particularly lenses made of silicone-containing polymer. The method of the invention comprising selectively depressurizing and pressurizing an entry hold chamber and an exit hold chamber while constantly maintaining a plasma gas i ...


5
Yasuo Matsuzawa, Nicolae Enciu, Celeste Aguado: Method and kits for sterilizing and storing soft contact lenses. Novartis, Jian Zhou, Robert A Ambrose, May 25, 2010: US07722808 (15 worldwide citation)

The present invention provides a method and a container for sterilizing a soft contact lens and for providing a sterilized storage package of the soft contact lens maintained in a packaging solution. By using the method and container of the invention, deformations of soft contact lenses during autoc ...


6
Yongxing Qiu, Lynn Cook Winterton, John Martin Lally, Yasuo Matsuzawa, Rafael Victor Andino, Allen Gilliard: Method for applying a coating to a medical device. Novartis, Jian Zhou, Robert J Gorman, R Scott Meece, February 22, 2005: US06858248 (12 worldwide citation)

This invention provides a method for efficiently applying a coating to each of a plurality of objects selected from the group consisting of ophthalmic lenses, molds for making ophthalmic lenses, and other medical devices, the method comprising dipping the plurality of objects into a coating bath con ...


7
Yasuo Matsuzawa, Hans I Wallsten, Hirotsugu K Yasuda: Apparatus and process for the treatment of powder particles for modifying the surface properties of the individual particles. Plasmacarb, Burns Doane Swecker & Mathis, January 11, 1994: US05278384 (11 worldwide citation)

An apparatus for low temperature plasma treatment of powder particles for modifying the surface properties thereof, comprising means for the creation of a low pressure zone and, in association therewith, at least one cascade arc torch generator to form a plasma torch which is directed into said low ...


8
Yasuo Matsuzawa, Lynn Cook Winterton: Lens plasma coating system. Novartis, Jian Zhou, Robert Gorman, R Scott Meece, April 19, 2005: US06881269 (10 worldwide citation)

The invention provides a system and method for plasma coating of an optical lens, particularly lenses made of silicone-containing polymer. A system of the invention comprises an entry chamber, a coating chamber downstream from the entry chamber, and an exit chamber downstream from the coating chambe ...


9
Ellen Marie Ajello, Michael Nelson Wilde, Yasuo Matsuzawa: Deblocking contact lenses. Novartis, Rob J Gorman, Jian S Zhou, R Scott Meece, September 6, 2005: US06939487 (10 worldwide citation)

A method and apparatus for removing a polymeric contact lens from a mold comprising lowering the temperature of the contact lens with a cryogenic material, such as liquid nitrogen, to a temperature and for a time sufficient for the lens to release from the mold without the application of external fo ...


10
Yasuo Matsuzawa: Method for applying a coating onto a silicone hydrogel lens. Novartis, Jian Zhou, October 25, 2011: US08044112 (9 worldwide citation)

The invention provides a cost-effective method for making a silicone hydrogel contact lens having an LbL coating thereon that is not covalently attached to the lens and has good hydrophilicity, intactness and durability. The method comprises LbL coating at high temperature.