1
Masayuki Yokoyama, Yasuhisa Sakurai, Teruo Okano, Kazunori Kataoka: Physical trapping type polymeric micelle drug preparation. Research Development Corporation of Japan, Pennie & Edmonds, September 12, 1995: US05449513 (100 worldwide citation)

The present invention relates to drug carriers composed of a block copolymer having hydrophilic and hydrophobic segments, a polymeric micelle type drug comprising hydrophobic drugs trapped by physical treatments in said drug carrier and methods for trapping hydrophobic drugs in the drug carrier. The ...


2
Masayuki Yokoyama, Yasuhisa Sakurai, Teruo Okano, Kazunori Kataoka: Physical trapping type polymeric micelle drug preparation. Research Development Corporation of Japan, Pennie & Edmonds, April 23, 1996: US05510103 (57 worldwide citation)

The present invention relates to drug carriers composed of a block copolymer having hydrophilic and hydrophobic segments, a polymeric micelle type drug comprising hydrophobic drugs trapped by physical treatments in said drug carrier and methods for trapping hydrophobic drugs in the drug carrier. The ...


3
Teruo Okano, Kazunori Kataoka, Noriko Yamada, Yasuhisa Sakurai, Takayuki Amiya, Akira Mamada: Bed material for cell culture. Kao Corporation, Tokyo Women s Medical College, Wenderoth Lind & Ponack, February 8, 1994: US05284766 (50 worldwide citation)

Disclosed is a bed material whereby cultured or grown cells are collected or detached from the material without a proteolysis enzyme or chemical material. The bed material comprises a support and a coating thereon, wherein the coating is formed from a polymer or copolymer which has a critical soluti ...


4
Yasuhisa Sakurai, Teruo Okano, Kazunori Kataoka, Noriko Yamada, Shohei Inoue, Masayuki Yokoyama: Water soluble high molecular weight polymerized drug preparation. Research Development Corp of Japan, Pennie & Edmonds, May 2, 1995: US05412072 (48 worldwide citation)

This invention is a water-soluble high molecular polymerized drug comprising a water-soluble clock copolymer having a hydrophilic segment and a hydrophobic pharmacological-functioning segment to side chain of which a drug is bonded. The hydrophilic first segments of the present invention include pol ...


5
Yasuhisa Sakurai, Teruo Okano, Kazunori Kataoka, Noriko Yamada, Shohei Inoue, Masayuki Yokoyama: Water soluble high molecular weight polymerized drug preparation. Research Development Corporation of Japan, Pennie & Edmonds, December 2, 1997: US05693751 (32 worldwide citation)

This invention is a water-soluble high molecular polymerized drug comprising a water-soluble clock copolymer having a hydrophilic segment and a hydrophobic pharmacological-functioning segment to side chain of which a drug is bonded.


6
Tsuyoshi Miyazaki, Yoshishige Murata, Daijiro Shiino, Kazunori Waki, Yasuhisa Sakurai, Teruo Okano, Kazunori Kataoka, Yoshiyuki Koyama, Masayuki Yokoyama, Shigeru Kitano: Polymers having benzeneboronic acid groups and insulin complexes of same of a sugar response type. Nippon Oil & Fats, Antonelli Terry Stout & Kraus, December 26, 1995: US05478575 (25 worldwide citation)

The present invention provides a polymer complex of a sugar response type having boronic acid groups in the polymer. Medicines may be contained or linked, preferably, the medicines have hydroxy groups. The polymer having boronic acid groups and the medicine having hydroxy groups may be linked by bor ...


7
Katsuro Shinoda, Toshiyuki Kawaguchi, Hiroyuki Katsukawa, Genzo Kimura, Naoki Tanaka, Hiroyuki Abe, Yasuhisa Sakurai: Apparatus for detecting faults on power transmission lines. NGK Insulators, Parkhurst Wendel & Rossi, April 13, 1993: US05202812 (20 worldwide citation)

In a system for transmitting an electrical power supply by means of an over-head power transmission line supported by power transmission towers, a fault such as a short-circuit fault and a ground fault is detected by providing optical current sensors having opto-magnetic elements and opto-electric f ...


8
Teruo Okano, Akihiko Kikuchi, Yasuhisa Sakurai, Hideko Kanazawa, Yoshikazu Matsushima: Packing material for chromatography having novel characteristic and method for isolation of substance using the same. Teruo Okano, Fish & Richardson P C, March 16, 2004: US06706187 (15 worldwide citation)

To provide chromatographic packings whereby biological components, etc. which cannot be separated by either ion-exchange chromatography or reversed phase chromatography employed alone can be efficiently separated without deteriorating their activities. Use is made of a packing which contains a charg ...


9
Teruo Okano, Akihiko Kikuchi, Yasuhisa Sakurai, Hideko Kanazawa, Yoshikazu Matsushima: Method for separating PTH amino acids. Amersham Pharmacia Biotech, Birch Stewart Kolasch & Birch, April 16, 2002: US06372141 (13 worldwide citation)

PTH-amino acids can be analyzed within a short time at a high sensitivity by chromatographically separating said PTH-amino acids with the use of a packing wherein the hydrophilic/hydrophobic balance on the stationary phase surface can be changed by an external signal while fixing the mobile phase to ...


10
Yasuhisa Sakurai, Teruo Okano, Masayuki Yokoyama, Kazunori Kataoka, Yukio Nagasaki, Nobuyuki Ohsako, Masao Kato: Polyether having heterofunctional groups at both ends, process for the preparation thereof and polymerization initiator therefor. Research Development Corporation of Japan, Pennie & Edmonds, January 9, 1996: US05483008 (9 worldwide citation)

The present invention relates to a bifunctional polyether having groups different from each other at both ends, with a polymerization degree of 5 to 10000 and consisting of repeating units each represented by the following formula (I): ##STR1## (wherein R.sub.1, represents a hydrogen atom, halogen a ...