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Wong Chi Huey, Brik Ashraf, Yang Yu Ying, Ficht Simon, Payne Richard: Method of preparing glycopeptides. The Scripps Research Institute, Wong Chi Huey, Brik Ashraf, Yang Yu Ying, Ficht Simon, Payne Richard, STEFFEY Charles E, October 4, 2007: WO/2007/111952 (17 worldwide citation)

A method is provided for the synthesis of glycopeptides using a sugar assisted ligation strategy, wherein an N-terminal peptide portion in the form of a thioester is coupled with a C-terminal peptide portion bearing a carbohydrate moiety comprising a thiol group.


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Wong Chi Huey, Brik Ashraf, Yang Yu Ying, Ficht Simon, Payne Richard: Method of preparing glycopeptides. Scripps Research Inst, December 3, 2008: EP1996609-A2 (12 worldwide citation)

A method is provided for the synthesis of glycopeptides using a sugar assisted ligation strategy, wherein an N-terminal peptide portion in the form of a thioester is coupled with a C-terminal peptide portion bearing a carbohydrate moiety comprising a thiol group.


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GU JIANXIN, KIM JIN HWAN, PRASAD A KRISHNA, YANG YU YING: PROCEDES DE GLYCOCONJUGAISON ET COMPOSITIONS, GLYCOCONJUGATION PROCESSES AND COMPOSITIONS. Pfizer, Pfizer, TORYS, November 15, 2016: CA2881420

The invention provides eTEC linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a (2-((2-oxoethyl)thio)ethyl)carbamate (eTEC) spacer, immunogenic compositions comprising such glycoconjugates, and methods for the preparation and use of such glycoconjugate ...