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Terrett Jonathan A, Pogue Sarah L, Toy Kristopher, Yang Lan, Rao Naik Chetana, Chen Bingliang: Human antibodies that bind mesothelin, and uses thereof. Medarex, Terrett Jonathan A, Pogue Sarah L, Toy Kristopher, Yang Lan, Rao Naik Chetana, Chen Bingliang, FEHLNER Paul F, April 9, 2009: WO/2009/045957 (10 worldwide citation)

The present disclosure provides isolated monoclonal antibodies that specifically bind to mesothelin with high affinity, particularly human monoclonal antibodies. Preferably, the antibodies bind human mesothelin. In certain embodiments, the antibodies are capable of internalizing into mesothelin-expr ...


2
Graziano Robert, Huang Haichun, Yang Lan, Toy Kristopher, Leblanc Heidi N: Human antibodies that bind multiple irta family proteins, and uses thereof. Medarex, Graziano Robert, Huang Haichun, Yang Lan, Toy Kristopher, Leblanc Heidi N, FEHLNER Paul F, September 12, 2008: WO/2008/109533 (5 worldwide citation)

The present disclosure provides isolated monoclonal antibodies that bind to multiple IRTA family proteins with high affinity, particularly human monoclonal antibodies. Preferred antibodies of the invention specifically bind an IRTA4 protein and at least one other IRTA family protein. Nucleic acid mo ...


3
Bender Steven Lee, Casperson Gerald Fries, Hu Lowe Dana Dan, Jiang Xin, Li Gang, North Michael Aidan, Wang Jianying, Wickman Grant, Brams Peter, Huang Haichun, Devaux Brigitte, Chen Haibin, Tanamachi Dawn M, Toy Kristopher, Yang Lan, Sproul Tim W, Yamanaka Mark: Alpha 5 - beta 1 antibodies and their uses. Medarex, Pfizer, Bender Steven Lee, Casperson Gerald Fries, Hu Lowe Dana Dan, Jiang Xin, Li Gang, North Michael Aidan, Wang Jianying, Wickman Grant, Brams Peter, Huang Haichun, Devaux Brigitte, Chen Haibin, Tanamachi Dawn M, Toy Kristopher, Yang Lan, Sproul Tim W, Yamanaka Mark, BRADY James W, August 13, 2009: WO/2009/100110 (5 worldwide citation)

The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin α5β1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells ...


4
Duan Xue, Lei Xiaodong, Yang Lan: A highly oriented, layered metal double hydroxides film and its preparing method. Beijing University Of Chemical Technology, Duan Xue, Lei Xiaodong, Yang Lan, BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY, May 18, 2006: WO/2006/050648 (4 worldwide citation)

The present invention relates to a highly oriented, layered metal double hydroxides (LDHs) and its biomimetic synthesis method. The film of LDHs is grown on polymer substrate, and its general formula is [M2 1-xM3+x (OH) 2] x+(CO3 2-) x/2 . y H2O. The crystal face (001) (or the crystal face ab) of th ...


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Rajpal Arvind, Devalaraja Madhav, Toy Kristopher, Yang Lan, Huang Halichun, Zhang Jun Z, Brams Peter, Devaux Brigitte, Passmore David B: Antibodies to il-6 and their uses. Medarex, Pfizer, Rajpal Arvind, Devalaraja Madhav, Toy Kristopher, Yang Lan, Huang Halichun, Zhang Jun Z, Brams Peter, Devaux Brigitte, Passmore David B, Brady James W, December 23, 2009: WO/2009/155180 (4 worldwide citation)

Antibodies and antigen-binding portions thereof that bind to human IL-6 are provided. Also provided are nucleic acids encoding such antibodies and antigen binding portions, methods of making such antibodies and antigen binding portions, compositions comprising such antibodies or antigen binding port ...


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Xu Xu, Bedian Vahe, Meaddough Erika, Huang Haichun, Yang Lan, Toy Kristopher, Srinivasan Mohan, Badkar Advait V: Cd44 antibodies. Medarex, Pfizer, Xu Xu, Bedian Vahe, Meaddough Erika, Huang Haichun, Yang Lan, Toy Kristopher, Srinivasan Mohan, Badkar Advait V, BRADY James W, July 3, 2008: WO/2008/079246 (2 worldwide citation)

The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to CD44, and that function to inhibit CD44. The invention also relates to heavy and light chain immunoglobulins derived from human CD44 antibodies and nucleic acid molecules encoding ...


8
BENDER STEVEN LEE, CASPERSON GERALD FRIES, HU LOWE DANA DAN, JIANG XIN, LI GANG, NORTH MICHAEL AIDAN, WANG JIANYING, WICKMAN GRANT, BRAMS PETER, HUANG HAICHUN, DEVAUX BRIGITTE, CHEN HAIBIN, TANAMACHI DAWN, TOY KRISTOPHER, YANG LAN, SPROUL TIM W, YAMANAKA MARK: [fr] Anticorps Alpha 5 - beta 1 et leurs utilisations, [de] Alpha-5-Beta-1-Antikörper und ihre Verwendungen, [en] Alpha 5 - beta 1 antibodies and their uses. SQUIBB BRISTOL MYERS CO, Pfizer, September 25, 2013: EP2641612-A1

[en] The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin +-51 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host c ...


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BENDER STEVEN LEE, CASPERSON GERALD FRIES, HU LOWE DANA DAN, JIANG XIN, LI GANG, NORTH MICHAEL AIDAN, WANG JIANYING, WICKMAN GRANT, BRAMS PETER, HUANG HAICHUN, DEVAUX BRIGITTE, CHEN HAIBIN, TANAMACHI DAWN, TOY KRISTOPHER, YANG LAN, SPROUL TIM W, YAMANAKA MARK: [fr] Anticorps Alpha 5 - bêta 1 et leurs utilisations, [de] Alpha-5-beta-1-Antikörper und deren Verwendungen, [en] Alpha 5 - beta 1 antibodies and their uses. SQUIBB BRISTOL MYERS CO, Pfizer, October 16, 2013: EP2650017-A2

[en] The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin +-51 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host c ...


10
Sheng Chung Lo, Chen Yang Lan, Wei Ming Chen, Tzu Hung Huang: Wave power generation system and hydraulic component thereof. Industrial Technology Research Institute, Locke Lord, Tim Tingkang Xia Esq, January 12, 2016: US09234493

A wave power generation system includes a power generation component and a hydraulic component. The hydraulic component includes a cylinder and a piston. The cylinder connects to the power generation component. The cylinder has an accommodation space and a vent located in the middle section of the a ...