1
Choi Ha Soon, Wang Zhicheng, Gray Nathanael Schiander, Gu Xiang Ju, He Xiaohui, He Yun, Jiang Tao, Liu Yi, Richmond Wendy, Sim Taebo, Yang Kunyong: Compounds and compositions as protein kinase inhibitors. Irm, Choi Ha Soon, Wang Zhicheng, Gray Nathanael Schiander, Gu Xiang Ju, He Xiaohui, He Yun, Jiang Tao, Liu Yi, Richmond Wendy, Sim Taebo, Yang Kunyong, REID Scott W, September 1, 2005: WO/2005/080393 (43 worldwide citation)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal act ...


2
Liu Hong, He Xiaohui, Choi Ha Soon, Yang Kunyong, Woodmansee David, Wang Zhicheng, Ellis David Archer, Wu Baogen, He Yun, Nguyen Truc Ngoc: Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. Irm, Liu Hong, He Xiaohui, Choi Ha Soon, Yang Kunyong, Woodmansee David, Wang Zhicheng, Ellis David Archer, Wu Baogen, He Yun, Nguyen Truc Ngoc, REID Scott W, May 4, 2006: WO/2006/047516 (17 worldwide citation)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).


3
Liu Hong, He Xiaohui, Phillips Dean, Zhu Xuefeng, Yang Kunyong, Lau Thomas, Wu Baogen, Xie Yongping, Nguyen Truc Ngoc, Wang Xing: Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. Irm, Liu Hong, He Xiaohui, Phillips Dean, Zhu Xuefeng, Yang Kunyong, Lau Thomas, Wu Baogen, Xie Yongping, Nguyen Truc Ngoc, Wang Xing, REID Scott W, June 26, 2008: WO/2008/076754 (9 worldwide citation)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).


4
He Xiaohui, Zhu Xuefeng, Yang Kunyong, Epple Robert, Liu Hong: Compounds and methods for modulating g protein-coupled receptors. Irm, He Xiaohui, Zhu Xuefeng, Yang Kunyong, Epple Robert, Liu Hong, Raymond Daniel E, January 21, 2010: WO/2010/008831 (4 worldwide citation)

The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with or mediated by G protein-coupled receptors, in particular G protein-coupled receptor 120.


5
He Xiaohui, Yang Kunyong, Liu Hong, Ellis David Archer: Azolopyrimidines as inhibitors of cannabinoid 1 activity. Irm, He Xiaohui, Yang Kunyong, Liu Hong, Ellis David Archer, REID Scott W, October 25, 2007: WO/2007/120454 (2 worldwide citation)

The invention provides compounds of formula (Ia), (Ic), (Ig) and (Ik), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).


6
Choi Ha Soon, Wang Zhicheng, Zhu Xuefeng, He Xiaohui, Yang Kunyong, Liu Hong: Compounds and compositions as inhibitors of cannabinoid receptor 1 activity. Irm, Choi Ha Soon, Wang Zhicheng, Zhu Xuefeng, He Xiaohui, Yang Kunyong, Liu Hong, RAYMOND Daniel E, September 18, 2008: WO/2008/112674 (1 worldwide citation)

The invention provides compounds of formula (I), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB 1).


7
Marsilje Thomas H Iii, Lu Wenshuo, Chen Bei, He Xiaohui, Jiang Songchun, Yang Kunyong: Compounds and compositions as kinase inhibitors. Irm, Marsilje Thomas H Iii, Lu Wenshuo, Chen Bei, He Xiaohui, Jiang Songchun, Yang Kunyong, Tongco Wu Emily, December 30, 2009: WO/2009/158431 (1 worldwide citation)

The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth fact ...


8
Wu Baogen, Nguyen Truc N, Ellis David A, He Xiaohui, Anaclerio Beth M, Yang Kunyong, Choi Ha Soon, Wang Zhicheng, Marsilje Thomas, He Yun: Phenyl-substituted pyrrolidones. Irm, Wu Baogen, Nguyen Truc N, Ellis David A, He Xiaohui, Anaclerio Beth M, Yang Kunyong, Choi Ha Soon, Wang Zhicheng, Marsilje Thomas, He Yun, ESKER Todd, August 3, 2006: WO/2006/081554 (1 worldwide citation)

The present invention relates to phenyl-substituted pyrrolidones and compounds related to phenyl-substituted pyrrolidones. One use of these compounds is for the inhibition of viruses, e.g., HIV. The invention further relates to methods of malting these compounds, methods of identifying the efficacy ...


9
MARSILJE III Thomas H, LU Wenshuo, CHEN Bei, HE Xiaohui, LEE Christian Cho Hua, JIANG Songchun, YANG Kunyong: [fr] COMPOSÉS ET COMPOSITIONS EN TANT QU’INHIBITEURS DE KINASE, [en] PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS. MARSILJE III Thomas H, LU Wenshuo, CHEN Bei, HE Xiaohui, LEE Christian Cho Hua, JIANG Songchun, YANG Kunyong, IRM, TONGCO WU Emily, January 7, 2010: WO/2010/002655 (1 worldwide citation)

[en] The invention provides novel pyrimidine derivatives of formula I and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insuli ...


10
Molteni Valentina, He Xiaohui, He Yun, Kreusch Andreas, Nabakka Juliet, Yang Kunyong: Bicyclic compounds and compositions as pdf inhibitors. Irm, May 3, 2006: EP1651643-A2

This invention is directed to novel bicyclic compounds, to the uses of these compounds in various medicinal applications, including treating disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections, and to pharmaceutical compositions comprising the ...