1
Yan John Y: Porous medicated stent. Advanced Cardiovascular System, November 4, 1998: EP0875218-A2 (144 worldwide citation)

A medicated prosthesis, such as a stent, is deployed in a human vessel. A metallic stent has a plurality of pores in the metal which are loaded with medication. When the stent is implanted into the vasculature of a patient, the medication in the stent dissipates into the tissue of the vasculature pr ...


2
Callol Joseph R, Yan John Y: Protective coating for a stent with intermediate radiopaque coating. Advanced Cardiovascular System, February 25, 1998: EP0824900-A2 (70 worldwide citation)

The invention relates to coated stents and the method of making them. A stent that is substantially radiolucent is at least partially coated with a radiopaque layer that makes the stent visible under X-ray or fluoroscopy. A protective layer is coated on the stent and the radiopaque layer to protect ...


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Yiwen Li, Weijia William Lu, Man Chee Kenneth Cheung, Dip Kei Keith Luk, Chi Yan John Leong: Bioactive and osteoporotic bone cement. Prosperous Kingdom, Jones Day, July 15, 2003: US06593394 (39 worldwide citation)

A composition for use as a bioactive bone cement having a powder component including strontium-containing hydroxy apatite and formulated to create a settable fluid substance when mixed with a liquid component. The liquid component includes a Bisphenol A diglycidylether dimethacrylate resin which whe ...


5
Yan John Y: Method of manufacturing a medicated porous metal prosthesis. Advanced Cardiovascular System, November 4, 1998: EP0875217-A2 (34 worldwide citation)

A method of manufacturing a medicated prosthesis such as a stent. The method includes forming a stent out of porous metal and loading a therapeutic agent into the pores of the metal. In one embodiment the stent is formed from a sintered metal wire, sheet, or tube and can include adding a coating to ...


6
Yan John, Sirhan Motasim, Cryer Brett, Bhat Vinayak D: Degradable implantable medical devices. Elixir Medical Corporation, Yan John, Sirhan Motasim, Cryer Brett, Bhat Vinayak D, HESLIN James M, October 12, 2006: WO/2006/108065 (34 worldwide citation)

Devices and methods are provided for an implantable medical device which is degradable over a clinically relevant period of time. The medical devices may have the form of implants, graft implants, vascular implants, non vascular implants, wound closure implants, sutures, drug delivery implants, biol ...


7
Bhat Vinayak D, Yan John: Devices delivering therapeutic agents and methods regarding the same. Avantec Vascular Corporation, Bhat Vinayak D, Yan John, BAINS Nena, February 5, 2004: WO/2004/010900 (29 worldwide citation)

Devices and methods for reducing, inhibiting, or treating restenosis and hyperplasia after intravascular intervention are provided. In particular, the present invention provides luminal prosthesis (13), which allow for sustained or controlled release of at least one therapeutic capable agent (28) wi ...


8
Sirhan Motasim, Yan John: Device for delivery of therepeutic agents. Avantec Vascular, October 29, 2003: EP1355588-A2 (28 worldwide citation)

A device and a method using the same, for reducing restenosis and hyperplasia after intravascular intervention. In particular, the present invention provides luminal prostheses which allow for controlled release of at least one therapeutic capable agent with increased efficacy to selected locations ...


9
Sirhan Motasim, Yan John: Delivery of therapeutic capable agents. Avantec Vascular, May 12, 2004: EP1416884-A2 (26 worldwide citation)

The present invention provides improved stents and other prostheses for delivering substances to vascular and other luminal and intracorporeal environments. In particular, the present invention provides for therapeutic capable agent eluting stents with minimized undesirable loss of the therapeutic c ...


10
Sirhan Motasim, Yan John: Devices for delivery of therapeutic agents with variable release profile. Avantec Vascular, May 12, 2004: EP1416885-A2 (26 worldwide citation)

The present invention provides improved stents and other prostheses for delivering substances to vascular and other luminal and intracorporeal environments. In particular, the present invention provides for therapeutic capable agent eluting stents with minimized undesirable loss of the therapeutic c ...